ISSCR :: Stem Cell Science : Stem Cell Science Literature 2004

Stem Cell Science Literature

2004 Literature Click on the month to see the literature published that month or scroll through the list.
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December 2004
Updated: January 04, 2005

Armstrong, L., Stojkovic, M., Dimmick, I., Ahmad, S., Stojkovic, P., Hole, N., and Lako, M. (2004). Phenotypic Characterization of Murine Primitive Hematopoietic Progenitor Cells Isolated on Basis of Aldehyde Dehydrogenase Activity . Stem Cells 22 , 1142-1151.

Arnhold, S., Klein, H., Semkova, I., Addicks, K., and Schraermeyer, U. (2004). Neurally Selected Embryonic Stem Cells Induce Tumor Formation after Long-Term Survival following Engraftment into the Subretinal Space . Invest Ophthalmol Vis Sci 45 , 4251-4255.

Ben-Hur, T., Idelson, M., Khaner, H., Pera, M., Reinhartz, E., Itzik, A., and Reubinoff, B. E. (2004). Transplantation of Human Embryonic Stem Cell-Derived Neural Progenitors Improves Behavioral Deficit in Parkinsonian Rats . Stem Cells 22 , 1246-1255.

Bertrand, J. Y., Giroux, S., Golub, R., Klaine, M., Jalil, A., Boucontet, L., Godin, I., and Cumano, A. (2004). Characterization of purified intraembryonic hematopoietic stem cells as a tool to define their site of origin . PNAS, 0402270102.

Brenner, S., Whiting-Theobald, N., Kawai, T., Linton, G. F., Rudikoff, A. G., Choi, U., Ryser, M. F., Murphy, P. M., Sechler, J. M. G., and Malech, H. L. (2004). CXCR4-Transgene Expression Significantly Improves Marrow Engraftment of Cultured Hematopoietic Stem Cells . Stem Cells 22 , 1128-1133.

Chavakis, E., Aicher, A., Heeschen, C., Sasaki, K.-i., Kaiser, R., El Makhfi, N., Urbich, C., Peters, T., Scharffetter-Kochanek, K., Zeiher, A. M. , et al. (2004). Role of {beta}2-integrins for homing and neovascularization capacity of endothelial progenitor cells . J Exp Med, jem.20041402.

Coraux, C., Nawrocki-Raby, B., Hinnrasky, J., Kileztky, C., Gaillard, D., Dani, C., and Puchelle, E. (2004). EMBRYONIC STEM CELLS GENERATE AIRWAY EPITHELIAL TISSUE . Am J Respir Cell Mol Biol, 2004-0079RC.

Davidoff, M. S., Middendorff, R., Enikolopov, G., Riethmacher, D., Holstein, A. F., and Muller, D. (2004). Progenitor cells of the testosterone-producing Leydig cells revealed . J Cell Biol 167 , 935-944.

De Falco, E., Porcelli, D., Torella, A. R., Straino, S., Iachininoto, M. G., Orlandi, A., Truffa, S., Biglioli, P., Napolitano, M., Capogrossi, M. C., and Pesce, M. (2004). SDF-1 involvement in endothelial phenotype and ischemia-induced recruitment of bone marrow progenitor cells . Blood 104 , 3472-3482.

Dvash, T., Mayshar, Y., Darr, H., McElhaney, M., Barker, D., Yanuka, O., Kotkow, K. J., Rubin, L. L., Benvenisty, N., and Eiges, R. (2004). Temporal gene expression during differentiation of human embryonic stem cells and embryoid bodies . Hum Reprod 19 , 2875-2883.

Elliott, S. T., Crider, D. G., Garham, C. P., Boheler, K. R., and Van Eyk, J. E. (2004). Two-dimensional gel electrophoresis database of murine R1 embryonic stem cells . Proteomics 4 , 3813-3832.

Gerecht-Nir, S., Osenberg, S., Nevo, O., Ziskind, A., Coleman, R., and Itskovitz-Eldor, J. (2004). Vascular Development in Early Human Embryos and in Teratomas Derived from Human Embryonic Stem Cells . Biol Reprod 71 , 2029-2036.

Gershengorn, M. C., Hardikar, A. A., Wei, C., Geras-Raaka, E., Marcus-Samuels, B., and Raaka, B. M. (2004). Epithelial-to-Mesenchymal Transition Generates Proliferative Human Islet Precursor Cells . Science 306 , 2261-2264.

Gothert, J. R., Gustin, S. E., Hall, M. A., Green, A. R., Gottgens, B., Izon, D. J., and Begley, C. G. (2004). In vivo fate tracing studies using the SCL stem cell enhancer: embryonic hematopoietic stem cells significantly contribute to adult hematopoiesis . Blood, 2004-2008-3037.

Goyama, S., Yamaguchi, Y., Imai, Y., Kawazu, M., Nakagawa, M., Asai, T., Kumano, K., Mitani, K., Ogawa, S., Chiba, S. , et al. (2004). The transcriptionally active form of AML1 is required for hematopoietic rescue of the AML1-deficient embryonic para-aortic splanchnopleural (P-Sp) region . Blood 104 , 3558-3564.

Hematti, P., Hong, B.-K., Ferguson, C., Adler, R., Hanawa, H., Sellers, S., Holt, I. E., Eckfeldt, C. E., Sharma, Y., Schmidt, M. , et al. (2004). Distinct Genomic Integration of MLV and SIV Vectors in Primate Hematopoietic Stem and Progenitor Cells . PLoS Biology 2 , e423.

Homma, R., Yoshikawa, H., Takeno, M., Kurokawa, M. S., Masuda, C., Takada, E., Tsubota, K., Ueno, S., and Suzuki, N. (2004). Induction of Epithelial Progenitors In Vitro from Mouse Embryonic Stem Cells and Application for Reconstruction of Damaged Cornea in Mice . Invest Ophthalmol Vis Sci 45 , 4320-4326.

Imitola, J., Raddassi, K., Park, K. I., Mueller, F.-J., Nieto, M., Teng, Y. D., Frenkel, D., Li, J., Sidman, R. L., Walsh, C. A. , et al. (2004). Directed migration of neural stem cells to sites of CNS injury by the stromal cell-derived factor 1{alpha}/CXC chemokine receptor 4 pathway . PNAS 101 , 18117-18122.

Israeli, D., Benchaouir, R., Ziaei, S., Rameau, P., Gruszczynski, C., Peltekian, E., Danos, O., and Garcia, L. (2004). FGF6 mediated expansion of a resident subset of cells with SP phenotype in the C2C12 myogenic line . J Cell Physiol 201 , 409-419.

Iwama, A., Oguro, H., Negishi, M., Kato, Y., Morita, Y., Tsukui, H., Ema, H., Kamijo, T., Katoh-Fukui, Y., Koseki, H. , et al. (2004). Enhanced self-renewal of hematopoietic stem cells mediated by the polycomb gene product Bmi-1 . Immunity 21 , 843-851.

Jadlowiec, J., Koch, H., Zhang, X., Campbell, P. G., Seyedain, M., and Sfeir, C. (2004). Phosphophoryn Regulates the Gene Expression and Differentiation of NIH3T3, MC3T3-E1, and Human Mesenchymal Stem Cells via the Integrin/MAPK Signaling Pathway . J Biol Chem 279 , 53323-53330.

Kawada, H., Fujita, J., Kinjo, K., Matsuzaki, Y., Tsuma, M., Miyatake, H., Muguruma, Y., Tsuboi, K., Itabashi, Y., Ikeda, Y. , et al. (2004). Non-hematopoietic mesenchymal stem cells can be mobilized and differentiate into cardiomyocytes after myocardial infarction . Blood 104 , 3581-3587.

Kim, H.-G., de Guzman, C. G., Swindle, C. S., Cotta, C. V., Gartland, L., Scott, E. W., and Klug, C. A. (2004). The ETS family transcription factor PU.1 is necessary for the maintenance of fetal liver hematopoietic stem cells . Blood 104 , 3894-3900.

Klees, R. F., Salasznyk, R. M., Kingsley, K., Williams, W. A., Boskey, A., and Plopper, G. E. (2004). Laminin-5 Induces Osteogenic Gene Expression in Human Mesenchymal Stem Cells through an ERK-dependent Pathway . Mol Biol Cell, E04-08-0695.

Kofidis, T., de Bruin, J. L., Yamane, T., Balsam, L. B., Lebl, D. R., Swijnenburg, R.-J., Tanaka, M., Weissman, I. L., and Robbins, R. C. (2004). Insulin-Like Growth Factor Promotes Engraftment, Differentiation, and Functional Improvement after Transfer of Embryonic Stem Cells for Myocardial Restoration . Stem Cells 22 , 1239-1245.

Kondo, T., and Raff, M. (2004). Chromatin remodeling and histone modification in the conversion of oligodendrocyte precursors to neural stem cells . Genes Dev 18 , 2963-2972.

Ku, H. T., Zhang, N., Kubo, A., O'Connor, R., Mao, M., Keller, G., and Bromberg, J. S. (2004). Committing Embryonic Stem Cells to Early Endocrine Pancreas In Vitro . Stem Cells 22 , 1205-1217.

Kuznetsov, S. A., Riminucci, M., Ziran, N., Tsutsui, T. W., Corsi, A., Calvi, L., Kronenberg, H. M., Schipani, E., Robey, P. G., and Bianco, P. (2004). The interplay of osteogenesis and hematopoiesis: expression of a constitutively active PTH/PTHrP receptor in osteogenic cells perturbs the establishment of hematopoiesis in bone and of skeletal stem cells in the bone marrow . J Cell Biol 167 , 1113-1122.

Lapidos, K. A., Chen, Y. E., Earley, J. U., Heydemann, A., Huber, J. M., Chien, M., Ma, A., and McNally, E. M. (2004). Transplanted hematopoietic stem cells demonstrate impaired sarcoglycan expression after engraftment into cardiac and skeletal muscle . J Clin Invest 114 , 1577-1585.

Lee, J. B., Song, J. M., Lee, J. E., Park, J. H., Kim, S. J., Kang, S. M., Kwon, J. N., Kim, M. K., Roh, S. I., and Yoon, H. S. (2004). Available human feeder cells for the maintenance of human embryonic stem cells . Reproduction 128 , 727-735.

Liste, I., Garcia-Garcia, E., and Martinez-Serrano, A. (2004). The Generation of Dopaminergic Neurons by Human Neural Stem Cells Is Enhanced by Bcl-XL, Both In Vitro and In Vivo . J Neurosci 24 , 10786-10795.

Luo, Q., Kang, Q., Si, W., Jiang, W., Park, J. K., Peng, Y., Li, X., Luu, H. H., Luo, J., Montag, A. G. , et al. (2004). Connective Tissue Growth Factor (CTGF) Is Regulated by Wnt and Bone Morphogenetic Proteins Signaling in Osteoblast Differentiation of Mesenchymal Stem Cells . J Biol Chem 279 , 55958-55968.

Merkle, F. T., Tramontin, A. D., Garcia-Verdugo, J. M., and Alvarez-Buylla, A. (2004). Radial glia give rise to adult neural stem cells in the subventricular zone . PNAS 101 , 17528-17532.

Micallef, S. J., Janes, M. E., Knezevic, K., Davis, R. P., Elefanty, A. G., and Stanley, E. G. (2004). Retinoic Acid Induces Pdx1-Positive Endoderm in Differentiating Mouse Embryonic Stem Cells . Diabetes, 54.02.05.db04-1191.

Morgan, H. D., Dean, W., Coker, H. A., Reik, W., and Petersen-Mahrt, S. K. (2004). Activation-induced Cytidine Deaminase Deaminates 5-Methylcytosine in DNA and Is Expressed in Pluripotent Tissues: IMPLICATIONS FOR EPIGENETIC REPROGRAMMING . J Biol Chem 279 , 52353-52360.

Nishimura, E. K., Granter, S. R., and Fisher, D. E. (2004). Mechanisms of Hair Graying: Incomplete Melanocyte Stem Cell Maintenance in the Niche . Science, 1099593.

Panepucci, R. A., Siufi, J. L. C., Silva, W. A., Jr., Proto-Siquiera, R., Neder, L., Orellana, M., Rocha, V., Covas, D. T., and Zago, M. A. (2004). Comparison of Gene Expression of Umbilical Cord Vein and Bone Marrow-Derived Mesenchymal Stem Cells . Stem Cells 22 , 1263-1278.

Rao, R. R., and Stice, S. L. (2004). Gene Expression Profiling of Embryonic Stem Cells Leads to Greater Understanding of Pluripotency and Early Developmental Events . Biol Reprod 71 , 1772-1778.

Schulz, T. C., Noggle, S. A., Palmarini, G. M., Weiler, D. A., Lyons, I. G., Pensa, K. A., Meedeniya, A. C. B., Davidson, B. P., Lambert, N. A., and Condie, B. G. (2004). Differentiation of Human Embryonic Stem Cells to Dopaminergic Neurons in Serum-Free Suspension Culture . Stem Cells 22 , 1218-1238.

Schuringa, J. J., Wu, K., Morrone, G., and Moore, M. A. S. (2004). Enforced Activation of STAT5A Facilitates the Generation of Embryonic Stem-Derived Hematopoietic Stem Cells That Contribute to Hematopoiesis In Vivo . Stem Cells 22 , 1191-1204.

Sherwood, R. I., Christensen, J. L., Weissman, I. L., and Wagers, A. J. (2004). Determinants of Skeletal Muscle Contributions from Circulating Cells, Bone Marrow Cells, and Hematopoietic Stem Cells . Stem Cells 22 , 1292-1304.

Shirai, T., Miyagi, S., Horiuchi, D., Okuda-Katayanagi, T., Nishimoto, M., Muramatsu, M., Sakamoto, Y., Nagata, M., Hagiwara, K., and Okuda, A. (2004). Identification of an enhancer that controls upregulation of fibronectin during differentiation of embryonic stem cells into extraembryonic endoderm . J Biol Chem, M410731200.

Simerly, C., Navara, C., Hwan Hyun, S., Chun Lee, B., Keun Kang, S., Capuano, S., Gosman, G., Dominko, T., Chong, K. Y., Compton, D. , et al. (2004). Embryogenesis and blastocyst development after somatic cell nuclear transfer in nonhuman primates: overcoming defects caused by meiotic spindle extraction . Dev Biol 276 , 237-252.

Sun, W., and Downing, J. R. (2004). Haploinsufficiency of AML1 results in a decrease in the number of LTR-HSCs while simultaneously inducing an increase in more mature progenitors . Blood 104 , 3565-3572.

Vitale-Cross, L., Amornphimoltham, P., Fisher, G., Molinolo, A. A., and Gutkind, J. S. (2004). Conditional Expression of K-ras in an Epithelial Compartment that Includes the Stem Cells Is Sufficient to Promote Squamous Cell Carcinogenesis . Cancer Res 64 , 8804-8807.

Zhang, P., Iwasaki-Arai, J., Iwasaki, H., Fenyus, M. L., Dayaram, T., Owens, B. M., Shigematsu, H., Levantini, E., Huettner, C. S., Lekstrom-Himes, J. A. , et al. (2004a). Enhancement of hematopoietic stem cell repopulating capacity and self-renewal in the absence of the transcription factor C/EBP alpha . Immunity 21 , 853-863.

Zhang, S., Wang, D., Estrov, Z., Raj, S., Willerson, J. T., and Yeh, E. T. H. (2004b). Both Cell Fusion and Transdifferentiation Account for the Transformation of Human Peripheral Blood CD34-Positive Cells Into Cardiomyocytes In Vivo . Circulation 110 , 3803-3807.

Zhang, S., Wang, D., Estrov, Z., Raj, S., Willerson, J. T., and Yeh, E. T. H. (2004c). Both Cell Fusion and Transdifferentiation Account for the Transformation of Human Peripheral Blood CD34-Positive Cells Into Cardiomyocytes In Vivo . Circulation 110 , 3803-3807.

November 2004
Updated: January 04, 2005

Bieberich, E., Silva, J., Wang, G., Krishnamurthy, K., and Condie, B. G. (2004). Selective apoptosis of pluripotent mouse and human stem cells by novel ceramide analogues prevents teratoma formation and enriches for neural precursors in ES cell-derived neural transplants . J Cell Biol 167 , 723-734.

Brusselmans, K., Bono, F., Collen, D., Herbert, J.-M., Carmeliet, P., and Dewerchin, M. (2004). A novel role for VEGF as an autocrine survival factor for embryonic stem cells during hypoxia . J Biol Chem, M406613200.

Chilton, P. M., Rezzoug, F., Ratajczak, M. Z., Fugier-Vivier, I., Ratajczak, J., Kucia, M., Huang, Y., Tanner, M. K., and Ildstad, S. T. (2004). Hematopoietic stem cells from NOD mice exhibit autonomous behavior and a competitive advantage in allogeneic recipients . Blood, 2004-2007-2757.

Do, J. T., and Scholer, H. R. (2004). Nuclei of Embryonic Stem Cells Reprogram Somatic Cells . Stem Cells 22 , 941-949.

Fahnert, B., Veijola, J., Roel, G., Karkkainen, M. K., Railo, A., Destree, O., Vainio, S., and Neubauer, P. (2004). Murine Wnt-1 with an Internal c-myc Tag Recombinantly Produced in Escherichia coli Can Induce Intracellular Signaling of the Canonical Wnt Pathway in Eukaryotic Cells . J Biol Chem 279 , 47520-47527.

Fernandes, K. J. L., McKenzie, I. A., Mill, P., Smith, K. M., Akhavan, M., Barnabe-Heider, F., Biernaskie, J., Junek, A., Kobayashi, N. R., Toma, J. G. , et al. (2004). A dermal niche for multipotent adult skin-derived precursor cells . Nature Cell Biology 6 , 1082-1093.

Fischbach, N. A., Rozenfeld, S., Shen, W., Fong, S., Chrobak, D., Ginzinger, D., Kogan, S. C., Radhakrishnan, A., Le Beau, M. M., Largman, C., and Lawrence, H. J. (2004). HOXB6 over-expression in murine bone marrow immortalizes a myelomonocytic precursor in vitro and causes hematopoietic stem cell expansion and acute myeloid leukemia in vivo . Blood, 2004-2004-1583.

Guthrie, S. M., Curtis, L. M., Mames, R. N., Simon, G. G., Grant, M. B., and Scott, E. W. (2004). The nitric oxide pathway modulates hemangioblast activity of adult hematopoietic stem cells . Blood, 2004-2009-3415.

Houghton, J., Stoicov, C., Nomura, S., Rogers, A. B., Carlson, J., Li, H., Cai, X., Fox, J. G., Goldenring, J. R., and Wang, T. C. (2004). Gastric Cancer Originating from Bone Marrow-Derived Cells . Science 306 , 1568-1571.

Jiang, S., Walker, L., Afentoulis, M., Anderson, D. A., Jauron-Mills, L., Corless, C. L., and Fleming, W. H. (2004). Transplanted human bone marrow contributes to vascular endothelium . PNAS 101 , 16891-16896.

Joseph, N. M., Mukouyama, Y.-s., Mosher, J. T., Jaegle, M., Crone, S. A., Dormand, E.-L., Lee, K.-F., Meijer, D., Anderson, D. J., and Morrison, S. J. (2004). Neural crest stem cells undergo multilineage differentiation in developing peripheral nerves to generate endoneurial fibroblasts in addition to Schwann cells . Development 131 , 5599-5612.

Kehler, J., Tolkunova, E., Koschorz, B., Pesce, M., Gentile, L., Boiani, M., Lomeli, H., Nagy, A., McLaughlin, K. J., Scholer, H. R., and Tomilin, A. (2004). Oct4 is required for primordial germ cell survival . EMBO Reports 5 , 1078-1083.

Kubota, H., Avarbock, M. R., and Brinster, R. L. (2004). Growth factors essential for self-renewal and expansion of mouse spermatogonial stem cells . PNAS 101 , 16489-16494.

Kurata, S.-i., Okuyama, T., Osada, M., Watanabe, T., Tomimori, Y., Sato, S., Iwai, A., Tsuji, T., Ikawa, Y., and Katoh, I. (2004). p51/p63 Controls Subunit {alpha}3 of the Major Epidermis Integrin Anchoring the Stem Cells to the Niche . J Biol Chem 279 , 50069-50077.

Li, L., Arman, E., Ekblom, P., Edgar, D., Murray, P., and Lonai, P. (2004). Distinct GATA6- and laminin-dependent mechanisms regulate endodermal and ectodermal embryonic stem cell fates . Development 131 , 5277-5286.

Martinat, C., Shendelman, S., Jonason, A., Leete, T., Beal, M. F., Yang, L., Floss, T., and Abeliovich, A. (2004). Sensitivity to Oxidative Stress in DJ-1-Deficient Dopamine Neurons: An ES- Derived Cell Model of Primary Parkinsonism . PLoS Biology 2 , e327.

Murashov, A. K., Pak, E. S., Hendricks, W. A., Owensby, J. P., Sierpinski, P. L., Tatko, L. M., and Fletcher, P. L. (2004). Directed differentiation of embryonic stem cells into dorsal interneurons . FASEB J, 04-2251fje.

Parsons, C. H., Szomju, B., and Kedes, D. H. (2004). Susceptibility of human fetal mesencyhmal stem cells to Kaposi's sarcoma-associated herpesvirus . Blood 104 , 2736-2738.

Plachta, N., Bibel, M., Tucker, K. L., and Barde, Y.-A. (2004). Developmental potential of defined neural progenitors derived from mouse embryonic stem cells . Development 131 , 5449-5456.

Ponsaerts, P., Brown, J. P., Van Den Plas, D., Van Den Eeden, L., Van Bockstaele, D. R., Jorens, P. G., Van Tendeloo, V. F., Merregaert, J., Singh, P. B., and Berneman, Z. N. (2004). Messenger RNA electroporation is highly efficient in mouse embryonic stem cells: successful FLPe- and Cre-mediated recombination . Gene Ther 11 , 1606-1610.

Richard, E., Robert, E., Cario-Andre, M., Ged, C., Geronimi, F., Gerson, S. L., De Verneuil, H., and Moreau-Gaudry, F. (2004). Hematopoietic stem cell gene therapy of murine protoporphyria by methylguanine-DNA-methyltransferase-mediated in vivo drug selection . Gene Ther 11 , 1638-1647.

Sakaguchi, Y., Sekiya, I., Yagishita, K., Ichinose, S., Shinomiya, K., and Muneta, T. (2004). Suspended cells from trabecular bone by collagenase digestion become virtually identical to mesenchymal stem cells obtained from marrow aspirates . Blood 104 , 2728-2735.

Singh, S. K., Hawkins, C., Clarke, I. D., Squire, J. A., Bayani, J., Hide, T., Henkelman, R. M., Cusimano, M. D., and Dirks, P. B. (2004). Identification of human brain tumour initiating cells . Nature 432 , 396-401.

Smits, E., Ponsaerts, P., Lenjou, M., Nijs, G., Van Bockstaele, D. R., Berneman, Z. N., and Van Tendeloo, V. F. (2004). RNA-based gene transfer for adult stem cells and T cells . Leukemia 18 , 1898-1902.

Wilson, A., Murphy, M. J., Oskarsson, T., Kaloulis, K., Bettess, M. D., Oser, G. M., Pasche, A.-C., Knabenhans, C., MacDonald, H. R., and Trumpp, A. (2004). c-Myc controls the balance between hematopoietic stem cell self-renewal and differentiation . Genes Dev 18 , 2747-2763.

Wynn, R. F., Hart, C. A., Corradi-Perini, C., O'Neill, L., Evans, C. A., Wraith, J. E., Fairbairn, L. J., and Bellantuono, I. (2004). A small proportion of mesenchymal stem cells strongly expresses functionally active CXCR4 receptor capable of promoting migration to bone marrow . Blood 104 , 2643-2645.

Xu, C., Jiang, J., Sottile, V., McWhir, J., Lebkowski, J., and Carpenter, M. K. (2004). Immortalized Fibroblast-Like Cells Derived from Human Embryonic Stem Cells Support Undifferentiated Cell Growth . Stem Cells 22 , 972-980.

Yang, L., Bryder, D., Adolfsson, J., Nygren, J., Mansson, R., Sigvardsson, M., and Jacobsen, S. E. W. (2004). Identification of Lin-Sca1+kit+CD34+Flt3- short-term hematopoietic stem cells capable of rapidly reconstituting and rescuing myeloablated recipients . Blood, 2004-2006-2159.

Yun, K., Mantani, A., Garel, S., Rubenstein, J., and Israel, M. A. (2004). Id4 regulates neural progenitor proliferation and differentiation in vivo . Development 131 , 5441-5448.

Zeng, X., Cai, J., Chen, J., Luo, Y., You, Z.-B., Fotter, E., Wang, Y., Harvey, B., Miura, T., Backman, C. , et al. (2004). Dopaminergic Differentiation of Human Embryonic Stem Cells . Stem Cells 22 , 925-940.

October 2004
Updated: January 04, 2005

Ahn, J. I., Lee, K. H., Shin, D. M., Shim, J. W., Kim, C. M., Kim, H., Lee, S. H., and Lee, Y. S. (2004). Temporal expression changes during differentiation of neural stem cells derived from mouse embryonic stem cell . J Cell Biochem 93 , 563.

Almeida-Porada, G., Porada, C. D., Chamberlain, J., Torabi, A., and Zanjani, E. D. (2004). Formation of human hepatocytes by human hematopoietic stem cells in sheep . Blood 104 , 2582-2590.

Asaoka, M., and Lin, H. (2004). Germline stem cells in the Drosophila ovary descend from pole cells in the anterior region of the embryonic gonad . Development 131 , 5079-5089.

Beslu, N., Krosl, J., Laurin, M., Mayotte, N., Humphries, K. R., and Sauvageau, G. (2004). Molecular interactions involved in HOXB4-induced activation of HSC self-renewal . Blood 104 , 2307-2314.

Besser, D. (2004). Expression of Nodal, Lefty-A, and Lefty-B in Undifferentiated Human Embryonic Stem Cells Requires Activation of Smad2/3 . J Biol Chem 279 , 45076-45084.

Calhoun, J. D., Rao, R. R., Warrenfeltz, S., Rekaya, R., Dalton, S., McDonald, J., and Stice, S. L. (2004). Transcriptional profiling of initial differentiation events in human embryonic stem cells . Biochem Biophys Res Commun 323 , 453-464.

Catena, R., Tiveron, C., Ronchi, A., Porta, S., Ferri, A., Tatangelo, L., Cavallaro, M., Favaro, R., Ottolenghi, S., Reinbold, R. , et al. (2004). Conserved POU Binding DNA Sites in the Sox2 Upstream Enhancer Regulate Gene Expression in Embryonic and Neural Stem Cells . J Biol Chem 279 , 41846-41857.

Clarke, C. L., Sandle, J., Parry, S. C., Reis-Filho, J. S., O'Hare, M. J., and Lakhani, S. R. (2004). Cytokeratin 5/6 in normal human breast: lack of evidence for a stem cell phenotype . J Pathol 204 , 147.

Consiglio, A., Gritti, A., Dolcetta, D., Follenzi, A., Bordignon, C., Gage, F. H., Vescovi, A. L., and Naldini, L. (2004). From the Cover: Robust in vivo gene transfer into adult mammalian neural stem cells by lentiviral vectors . PNAS 101 , 14835-14840.

Fernandez, M., Pirondi, S., Manservigi, M., Giardino, L., and Calza, L. (2004). Thyroid hormone participates in the regulation of neural stem cells and oligodendrocyte precursor cells in the central nervous system of adult rat . Eur J Neurosci 20 , 2059-2070.

Galli, R., Binda, E., Orfanelli, U., Cipelletti, B., Gritti, A., De Vitis, S., Fiocco, R., Foroni, C., Dimeco, F., and Vescovi, A. (2004). Isolation and Characterization of Tumorigenic, Stem-like Neural Precursors from Human Glioblastoma . Cancer Res 64 , 7011-7021.

Gilboa, L., and Lehmann, R. (2004). How different is Venus from Mars? The genetics of germ-line stem cells in Drosophila females and males . Development 131 , 4895-4905.

Grassi, F., Pagani, F., Spinelli, G., De Angelis, L., Cossu, G., and Eusebi, F. (2004). Fusion-independent expression of functional ACh receptors in mouse mesoangioblast stem cells contacting muscle cells . J Physiol (Lond) 560 , 479-489.

Hansson, M., Tonning, A., Frandsen, U., Petri, A., Rajagopal, J., Englund, M. C. O., Heller, R. S., Hakansson, J., Fleckner, J., Skold, H. N. , et al. (2004). Artifactual Insulin Release From Differentiated Embryonic Stem Cells . Diabetes 53 , 2603-2609.

He, X. C., Zhang, J., Tong, W. G., Tawfik, O., Ross, J., Scoville, D. H., Tian, Q., Zeng, X., He, X., Wiedemann, L. M. , et al. (2004a). BMP signaling inhibits intestinal stem cell self-renewal through suppression of Wnt-beta-catenin signaling . Nat Genet 36 , 1117-1121.

He, X. C., Zhang, J., Tong, W.-G., Tawfik, O., Ross, J., Scoville, D. H., Tian, Q., Zeng, X., He, X., Wiedemann, L. M. , et al. (2004b). BMP signaling inhibits intestinal stem cell self-renewal through suppression of Wnt[ndash][beta]-catenin signaling . Nature Genetics 36 , 1117-1121.

Heine, W., Conant, K., Griffin, J. W., and Hoke, A. (2004). Transplanted neural stem cells promote axonal regeneration through chronically denervated peripheral nerves . Experimental Neurology 189 , 231-240.

Hock, H., Hamblen, M. J., Rooke, H. M., Schindler, J. W., Saleque, S., Fujiwara, Y., and Orkin, S. H. (2004). Gfi-1 restricts proliferation and preserves functional integrity of haematopoietic stem cells . Nature 431 , 1002-1007.

Hock, H., Meade, E., Medeiros, S., Schindler, J. W., Valk, P. J. M., Fujiwara, Y., and Orkin, S. H. (2004). Tel/Etv6 is an essential and selective regulator of adult hematopoietic stem cell survival . Genes Dev 18 , 2336-2341.

Hong, Y., and Stambrook, P. J. (2004). Restoration of an absent G1 arrest and protection from apoptosis in embryonic stem cells after ionizing radiation . PNAS 101 , 14443-14448.

Ikeda, R., Kurokawa, M. S., Chiba, S., Yoshikawa, H., Hashimoto, T., Tadokoro, M., and Suzuki, N. (2004). Transplantation of motoneurons derived from MASH1-transfected mouse ES cells reconstitutes neural networks and improves motor function in hemiplegic mice . Experimental Neurology 189 , 280-292.

Ishibashi, S., Sakaguchi, M., Kuroiwa, T., Yamasaki, M., Kanemura, Y., Shizuko, I., Shimazaki, T., Onodera, M., Okano, H., and Mizusawa, H. (2004). Human neural stem/progenitor cells, expanded in long-term neurosphere culture, promote functional recovery after focal ischemia in Mongolian gerbils . J Neurosci Res 78 , 215-223.

Jackson, M., Krassowska, A., Gilbert, N., Chevassut, T., Forrester, L., Ansell, J., and Ramsahoye, B. (2004). Severe global DNA hypomethylation blocks differentiation and induces histone hyperacetylation in embryonic stem cells . Mol Cell Biol 24 , 8862-8871.

Kehat, I., Khimovich, L., Caspi, O., Gepstein, A., Shofti, R., Arbel, G., Huber, I., Satin, J., Itskovitz-Eldor, J., and Gepstein, L. (2004). Electromechanical integration of cardiomyocytes derived from human embryonic stem cells . Nat Biotechnol 22 , 1282-1289.

Ling, K.-W., Ottersbach, K., van Hamburg, J. P., Oziemlak, A., Tsai, F.-Y., Orkin, S. H., Ploemacher, R., Hendriks, R. W., and Dzierzak, E. (2004). GATA-2 Plays Two Functionally Distinct Roles during the Ontogeny of Hematopoietic Stem Cells . J Exp Med 200 , 871-882.

Matsuoka, Y., Kubota, H., Adachi, E., Nagai, N., Marutani, T., Hosokawa, N., and Nagata, K. (2004). Insufficient Folding of Type IV Collagen and Formation of Abnormal Basement Membrane-like Structure in Embryoid Bodies Derived from Hsp47-Null Embryonic Stem Cells . Mol Biol Cell 15 , 4467-4475.

Messina, E., De Angelis, L., Frati, G., Morrone, S., Chimenti, S., Fiordaliso, F., Salio, M., Battaglia, M., Latronico, M. V. G., Coletta, M. , et al. (2004). Isolation and Expansion of Adult Cardiac Stem Cells From Human and Murine Heart . Circ Res 95 , 911-921.

Roh, C., Tao, Q., and Lyle, S. (2004). Dermal papilla-induced hair differentiation of adult epithelial stem cells from human skin . Physiol Genomics 19 , 207-217.

Ryu, B. Y., Orwig, K. E., Kubota, H., Avarbock, M. R., and Brinster, R. L. (2004). Phenotypic and functional characteristics of spermatogonial stem cells in rats . Dev Biol 274 , 158-170.

Soares, S., and Sotelo, C. (2004). Adult neural stem cells from the mouse subventricular zone are limited in migratory ability compared to progenitor cells of similar origin . Neuroscience 128 , 817.

Song, S., Witek, R. P., Lu, Y., Choi, Y. K., Zheng, D., Jorgensen, M., Li, C., Flotte, T. R., and Petersen, B. E. (2004). Ex vivo transduced liver progenitor cells as a platform for gene therapy in mice . Hepatology 40 , 918-924.

Venezia, T. A., Merchant, A. A., Ramos, C. A., Whitehouse, N. L., Young, A. S., Shaw, C. A., and Goodell, M. A. (2004). Molecular Signatures of Proliferation and Quiescence in Hematopoietic Stem Cells . PLoS Biology 2 , e301.

Vercauteren, S. M., and Sutherland, H. J. (2004). Constitutively active Notch4 promotes early human hematopoietic progenitor cell maintenance while inhibiting differentiation and causes lymphoid abnormalities in vivo . Blood 104 , 2315-2322.

Wang, D., Park, J. S., Chu, J. S. F., Krakowski, A., Luo, K., Chen, D. J., and Li, S. (2004). Proteomic Profiling of Bone Marrow Mesenchymal Stem Cells upon Transforming Growth Factor {beta}1 Stimulation . J Biol Chem 279 , 43725-43734.

Zeng, H., Yucel, R., Kosan, C., Klein-Hitpass, L., and Moroy, T. (2004). Transcription factor Gfi1 regulates self-renewal and engraftment of hematopoietic stem cells . EMBO J 23 , 4116-4125.

September 2004
Updated: January 04, 2005

Ader, M., Schachner, M., and Bartsch, U. (2004). Integration and differentiation of neural stem cells after transplantation into the dysmyelinated central nervous system of adult mice . Eur J Neurosci 20 , 1205-1210.

Amoh, Y., Li, L., Yang, M., Moossa, A. R., Katsuoka, K., Penman, S., and Hoffman, R. M. (2004). Nascent blood vessels in the skin arise from nestin-expressing hair-follicle cells . PNAS 101 , 13291-13295.

Arikawa, T., Omura, K., and Morita, I. (2004). Regulation of bone morphogenetic protein-2 expression by endogenous prostaglandin E2 in human mesenchymal stem cells . J Cell Physiol 200 , 400-406.

Bani-Yaghoub, M., Kendall, S. E., Moore, D. P., Bellum, S., Cowling, R. A., Nikopoulos, G. N., Kubu, C. J., Vary, C., and Verdi, J. M. (2004). Insulin acts as a myogenic differentiation signal for neural stem cells with multilineage differentiation potential . Development 131 , 4287-4298.

Bibel, M., Richter, J., Schrenk, K., Tucker, K. L., Staiger, V., Korte, M., Goetz, M., and Barde, Y.-A. (2004). Differentiation of mouse embryonic stem cells into a defined neuronal lineage . Nature Neuroscience 7 , 1003-1009.

Bielby, R. C., Boccaccini, A. R., Polak, J. M., and Buttery, L. D. (2004). In vitro differentiation and in vivo mineralization of osteogenic cells derived from human embryonic stem cells . Tissue Eng 10 , 1518-1525.

Blanpain, C., Lowry, W. E., Geoghegan, A., Polak, L., and Fuchs, E. (2004). Self-Renewal, Multipotency, and the Existence of Two Cell Populations within an Epithelial Stem Cell Niche . Cell 118 , 635-648.

Blelloch, R. H., Hochedlinger, K., Yamada, Y., Brennan, C., Kim, M., Mintz, B., Chin, L., and Jaenisch, R. (2004). Inaugural Article: Nuclear cloning of embryonal carcinoma cells . PNAS 101 , 13985-13990.

Botta, R., Gao, E., Stassi, G., Bonci, D., Pelosi, E., Zwas, D., Patti, M., Colonna, L., Baiocchi, M., Coppola, S. , et al. (2004). Heart infarct in NOD-SCID mice: Therapeutic vasculogenesis by transplantation of human CD34+ cells and low dose CD34+KDR+ cells . FASEB J 18 , 1392-1394.

Buytaert-Hoefen, K. A., Alvarez, E., and Freed, C. R. (2004). Generation of Tyrosine Hydroxylase Positive Neurons from Human Embryonic Stem Cells after Coculture with Cellular Substrates and Exposure to GDNF . Stem Cells 22 , 669-674.

Carotta, S., Pilat, S., Mairhofer, A., Schmidt, U., Dolznig, H., Steinlein, P., and Beug, H. (2004). Directed differentiation and mass cultivation of pure erythroid progenitors from mouse embryonic stem cells . Blood 104 , 1873-1880.

Challen, G. A., Martinez, G., Davis, M. J., Taylor, D. F., Crowe, M., Teasdale, R. D., Grimmond, S. M., and Little, M. H. (2004). Identifying the Molecular Phenotype of Renal Progenitor Cells . J Am Soc Nephrol 15 , 2344-2357.

Chute, J. P., Muramoto, G. G., Fung, J., and Oxford, C. (2004). Soluble factors elaborated by human brain endothelial cells induce the concomitant expansion of purified human BM CD34+CD38- cells and SCID repopulating cells . Blood, 2004-2004-1467.

Colombo, E., Galli, R., Cossu, G., Gecz, J., and Broccoli, V. (2004). Mouse orthologue of ARX, a gene mutated in several X-linked forms of mental retardation and epilepsy, is a marker of adult neural stem cells and forebrain GABAergic neurons . Dev Dyn 231 , 631-639.

Daheron, L., Opitz, S. L., Zaehres, H., Lensch, W. M., Andrews, P. W., Itskovitz-Eldor, J., and Daley, G. Q. (2004). LIF/STAT3 Signaling Fails to Maintain Self-Renewal of Human Embryonic Stem Cells . Stem Cells 22 , 770-778.

Etheridge, S. L., Spencer, G. J., Heath, D. J., and Genever, P. G. (2004). Expression profiling and functional analysis of wnt signaling mechanisms in mesenchymal stem cells . Stem Cells 22 , 849-860.

Harrison, J., Melville, A. J., Forsythe, J. S., Muddle, B. C., Trounson, A. O., Gross, K. A., and Mollard, R. (2004a). Sintered hydroxyfluorapatites-IV: the effect of fluoride substitutions upon colonisation of hydroxyapatites by mouse embryonic stem cells . Biomaterials 25 , 4977-4986.

Harrison, J., Pattanawong, S., Forsythe, J. S., Gross, K. A., Nisbet, D. R., Beh, H., Scott, T. F., Trounson, A. O., and Mollard, R. (2004b). Colonization and maintenance of murine embryonic stem cells on poly( [Formula: see text] -hydroxy esters) . Biomaterials 25 , 4963-4970.

Hattori, N., Abe, T., Hattori, N., Suzuki, M., Matsuyama, T., Yoshida, S., Li, E., and Shiota, K. (2004). Preference of DNA Methyltransferases for CpG Islands in Mouse Embryonic Stem Cells . Genome Res 14 , 1733-1740.

Hermann, A., Gastl, R., Liebau, S., Popa, M. O., Fiedler, J., Boehm, B. O., Maisel, M., Lerche, H., Schwarz, J., Brenner, R., and Storch, A. (2004). Efficient generation of neural stem cell-like cells from adult human bone marrow stromal cells . J Cell Sci 117 , 4411-4422.

Hess, D. A., Meyerrose, T. E., Wirthlin, L., Craft, T. P., Herrbrich, P. E., Creer, M. H., and Nolta, J. A. (2004). Functional characterization of highly purified human hematopoietic repopulating cells isolated according to aldehyde dehydrogenase activity . Blood 104 , 1648-1655.

Hirschmann-Jax, C., Foster, A. E., Wulf, G. G., Nuchtern, J. G., Jax, T. W., Gobel, U., Goodell, M. A., and Brenner, M. K. (2004). A distinct "side population" of cells with high drug efflux capacity in human tumor cells . PNAS 101 , 14228-14233.

Hu, X., Jin, L., and Feng, L. (2004). Erk1/2 but not PI3K pathway is required for neurotrophin 3-induced oligodendrocyte differentiation of post-natal neural stem cells . J Neurochem 90 , 1339-1347.

Laplante, I., Beliveau, R., and Paquin, J. (2004). RhoA/ROCK and Cdc42 regulate cell-cell contact and N-cadherin protein level during neurodetermination of P19 embryonal stem cells . J Neurobiol 60 , 289-307.

Lemoli, R. M., Ferrari, D., Fogli, M., Rossi, L., Pizzirani, C., Forchap, S., Chiozzi, P., Vaselli, D., Bertolini, F., Foutz, T. , et al. (2004). Extracellular nucleotides are potent stimulators of human hematopoietic stem cells in vitro and in vivo . Blood 104 , 1662-1670.

Lo, K. C., Lei, Z., Rao, C. V., Beck, J., and Lamb, D. J. (2004). De Novo Testosterone Production in Luteinizing Hormone Receptor Knockout Mice after Transplantation of Leydig Stem Cells . Endocrinology 145 , 4011-4015.

Matin, M. M., Walsh, J. R., Gokhale, P. J., Draper, J. S., Bahrami, A. R., Morton, I., Moore, H. D., and Andrews, P. W. (2004). Specific Knockdown of Oct4 and {beta}2-microglobulin Expression by RNA Interference in Human Embryonic Stem Cells and Embryonic Carcinoma Cells . Stem Cells 22 , 659-668.

McKinney-Freeman, S., and Goodell, M. A. (2004). Circulating hematopoietic stem cells do not efficiently home to bone marrow during homeostasis . Exp Hematol 32 , 868-876.

Miles, G. B., Yohn, D. C., Wichterle, H., Jessell, T. M., Rafuse, V. F., and Brownstone, R. M. (2004). Functional Properties of Motoneurons Derived from Mouse Embryonic Stem Cells . J Neurosci 24 , 7848-7858.

Nemeth, M. J., Cline, A. P., Anderson, S. M., Garrett-Beal, L. J., and Bodine, D. M. (2004). Hmgb3 deficiency deregulates proliferation and differentiation of common lymphoid and myeloid progenitors . Blood.

Oliver, J. A., Maarouf, O., Cheema, F. H., Martens, T. P., and Al-Awqati, Q. (2004). The renal papilla is a niche for adult kidney stem cells . J Clin Invest 114 , 795-804.

Otani, A., Dorrell, M. I., Kinder, K., Moreno, S. K., Nusinowitz, S., Banin, E., Heckenlively, J., and Friedlander, M. (2004). Rescue of retinal degeneration by intravitreally injected adult bone marrow-derived lineage-negative hematopoietic stem cells . J Clin Invest 114 , 765-774.

Roeder, I., Kamminga, L. M., Braesel, K., Dontje, B., de Haan, G., and Loeffler, M. (2004). Competitive clonal hematopoiesis in mouse chimeras explained by a stochastic model of stem cell organization . Blood, 2004-2001-0282.

Sanchez, A., Factor, V. M., Espinoza, L. A., Schroeder, I. S., and Thorgeirsson, S. S. (2004). In vitro differentiation of rat liver derived stem cells results in sensitization to TNFalpha-mediated apoptosis . Hepatology 40 , 590-599.

Schlaeger, T. M., Schuh, A., Flitter, S., Fisher, A., Mikkola, H., Orkin, S. H., Vyas, P., and Porcher, C. (2004). Decoding hematopoietic specificity in the helix-loop-helix domain of the transcription factor SCL/Tal-1 . Mol Cell Biol 24 , 7491-7502.

Schuringa, J. J., Chung, K. Y., Morrone, G., and Moore, M. A. (2004). Constitutive Activation of STAT5A Promotes Human Hematopoietic Stem Cell Self-Renewal and Erythroid Differentiation . J Exp Med 200 , 623-635.

Seaberg, R. M., Smukler, S. R., Kieffer, T. J., Enikolopov, G., Asghar, Z., Wheeler, M. B., Korbutt, G., and van der Kooy, D. (2004). Clonal identification of multipotent precursors from adult mouse pancreas that generate neural and pancreatic lineages . Nat Biotechnol 22 , 1115-1124.

Setoguchi, T., and Kondo, T. (2004). Nuclear export of OLIG2 in neural stem cells is essential for ciliary neurotrophic factor-induced astrocyte differentiation . J Cell Biol 166 , 963-968.

Sinor, A. D., and Lillien, L. (2004). Akt-1 expression level regulates CNS precursors . J Neurosci 24 , 8531-8541.

Smith, J. R., Pochampally, R., Perry, A., Hsu, S. C., and Prockop, D. J. (2004). Isolation of a highly clonogenic and multipotential subfraction of adult stem cells from bone marrow stroma . Stem Cells 22 , 823-831.

Smith, L. E. H. (2004). Bone marrow-derived stem cells preserve cone vision in retinitis pigmentosa . J Clin Invest 114 , 755-757.

Sowa, H., Kaji, H., Hendy, G. N., Canaff, L., Komori, T., Sugimoto, T., and Chihara, K. (2004). Menin Is Required for Bone Morphogenetic Protein 2- and Transforming Growth Factor {beta}-regulated Osteoblastic Differentiation through Interaction with Smads and Runx2 . J Biol Chem 279 , 40267-40275.

Stojkovic, M., Lako, M., Stojkovic, P., Stewart, R., Przyborski, S., Armstrong, L., Evans, J., Herbert, M., Hyslop, L., Ahmad, S. , et al. (2004). Derivation of human embryonic stem cells from day-8 blastocysts recovered after three-step in vitro culture . Stem Cells 22 , 790-797.

Su, X., Kameoka, S., Lentz, S., and Majumder, S. (2004). Activation of REST/NRSF Target Genes in Neural Stem Cells Is Sufficient To Cause Neuronal Differentiation . Mol Cell Biol 24 , 8018-8025.

Sumi, T., Fujimoto, Y., Nakatsuji, N., and Suemori, H. (2004). STAT3 Is Dispensable for Maintenance of Self-Renewal in Nonhuman Primate Embryonic Stem Cells . Stem Cells 22 , 861-872.

Summers, Y. J., Heyworth, C. M., De Wynter, E. A., Hart, C. A., Chang, J., and Testa, N. G. (2004). AC133+ G0 Cells from Cord Blood Show a High Incidence of Long-Term Culture-Initiating Cells and a Capacity for More Than 100 Million-Fold Amplification of Colony-Forming Cells In Vitro . Stem Cells 22 , 704-715.

Tagliafico, E., Brunelli, S., Bergamaschi, A., De Angelis, L., Scardigli, R., Galli, D., Battini, R., Bianco, P., Ferrari, S., and Cossu, G. (2004). TGF{beta}/BMP activate the smooth muscle/bone differentiation programs in mesoangioblasts . J Cell Sci 117 , 4377-4388.

Takito, J., and Al-Awqati, Q. (2004). Conversion of ES cells to columnar epithelia by hensin and to squamous epithelia by laminin . J Cell Biol 166 , 1093-1102.

Ueda, K., Hanazono, Y., Shibata, H., Ageyama, N., Ueda, Y., Ogata, S., Tabata, T., Nagashima, T., Takatoku, M., Kume, A. , et al. (2004). High-Level in Vivo Gene Marking after Gene-Modified Autologous Hematopoietic Stem Cell Transplantation without Marrow Conditioning in Nonhuman Primates . Mol Ther 10 , 469-477.

Vanderluit, J. L., Ferguson, K. L., Nikoletopoulou, V., Parker, M., Ruzhynsky, V., Alexson, T., McNamara, S. M., Park, D. S., Rudnicki, M., and Slack, R. S. (2004). p107 regulates neural precursor cells in the mammalian brain . J Cell Biol 166 , 853-863.

Vodyanik, M. A., Bork, J. A., Thomson, J. A., and Slukvin, I. I. (2004). Human embryonic stem cell-derived CD34+ cells: efficient production in the co-culture with OP9 stromal cells and analysis of lymphohematopoietic potential . Blood, 2004-2004-1649.

Yoshida, T., Kawai-Kowase, K., and Owens, G. K. (2004). Forced Expression of Myocardin Is Not Sufficient for Induction of Smooth Muscle Differentiation in Multipotential Embryonic Cells . Arterioscler Thromb Vasc Biol 24 , 1596-1601.

Zimmermann, S., Glaser, S., Ketteler, R., Waller, C. F., Klingmuller, U., and Martens, U. M. (2004). Effects of telomerase modulation in human hematopoietic progenitor cells . Stem Cells 22 , 741-749.

August 2004
Updated: January 04, 2005

Adams, D. J., Biggs, P. J., Cox, T., Davies, R., Van Der Weyden, L., Jonkers, J., Smith, J., Plumb, B., Taylor, R., Nishijima, I. , et al. (2004). Mutagenic Insertion and Chromosome Engineering Resource (MICER) . Nat Genet 36 , 867-871.

Baumann, C. I., Bailey, A. S., Li, W., Ferkowicz, M. J., Yoder, M. C., and Fleming, W. H. (2004). PECAM-1 is expressed on hematopoietic stem cells throughout ontogeny and identifies a population of erythroid progenitors . Blood 104 , 1010-1016.

Belicchi, M., Pisati, F., Lopa, R., Porretti, L., Fortunato, F., Sironi, M., Scalamogna, M., Parati, E. A., Bresolin, N., and Torrente, Y. (2004). Human skin-derived stem cells migrate throughout forebrain and differentiate into astrocytes after injection into adult mouse brain . J Neurosci Res 77 , 475-486.

Booth, H. A., and Holland, P. W. (2004). Eleven daughters of NANOG . Genomics 84 , 229-238.

Bunting, K. D., Yu, W.-M., Bradley, H. L., Haviernikova, E., Kelly-Welch, A. E., Keegan, A. D., and Qu, C.-K. (2004). Increased numbers of committed myeloid progenitors but not primitive hematopoietic stem/progenitors in mice lacking STAT6 expression . J Leukoc Biol 76 , 484-490.

Ceradini, D. J., Kulkarni, A. R., Callaghan, M. J., Tepper, O. M., Bastidas, N., Kleinman, M. E., Capla, J. M., Galiano, R. D., Levine, J. P., and Gurtner, G. C. (2004). Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1 . Nat Med 10 , 858-864.

Cheng, A., Tang, H., Cai, J., Zhu, M., Zhang, X., Rao, M., and Mattson, M. P. (2004). Gap junctional communication is required to maintain mouse cortical neural progenitor cells in a proliferative state . Dev Biol 272 , 203-216.

Christopherson, K. W., II, Hangoc, G., Mantel, C. R., and Broxmeyer, H. E. (2004). Modulation of Hematopoietic Stem Cell Homing and Engraftment by CD26 . Science 305 , 1000-1003.

Conn, C. W., Lewellyn, A. L., and Maller, J. L. (2004). The DNA Damage Checkpoint in Embryonic Cell Cycles Is Dependent on the DNA-to-Cytoplasmic Ratio . Dev Cell 7 , 275-281.

de Sousa Lopes, S. M. C., Roelen, B. A. J., Monteiro, R. M., Emmens, R., Lin, H. Y., Li, E., Lawson, K. A., and Mummery, C. L. (2004). BMP signaling mediated by ALK2 in the visceral endoderm is necessary for the generation of primordial germ cells in the mouse embryo . Genes Dev 18 , 1838-1849.

Ding, W., Bai, J., Zhang, J., Chen, Y., Cao, L., He, Y., Shen, L., Wang, F., and Tian, J. (2004). In vivo tracking of implanted stem cells using radio-labeled transferrin scintigraphy . Nucl Med Biol 31 , 719-725.

Ferri, A. L. M., Cavallaro, M., Braida, D., Di Cristofano, A., Canta, A., Vezzani, A., Ottolenghi, S., Pandolfi, P. P., Sala, M., DeBiasi, S., and Nicolis, S. K. (2004). Sox2 deficiency causes neurodegeneration and impaired neurogenesis in the adult mouse brain . Development 131 , 3805-3819.

Ferron, S., Mira, H., Franco, S., Cano-Jaimez, M., Bellmunt, E., Ramirez, C., Farinas, I., and Blasco, M. A. (2004). Telomere shortening and chromosomal instability abrogates proliferation of adult but not embryonic neural stem cells . Development 131 , 4059-4070.

Furuyama, T., Kitayama, K., Shimoda, Y., Ogawa, M., Sone, K., Yoshida-Araki, K., Hisatsune, H., Nishikawa, S., Nakayama, K., Ikeda, K. , et al. (2004). Abnormal Angiogenesis in Foxo1 (Fkhr)-deficient Mice . J Biol Chem 279 , 34741-34749.

Gajavelli, S., Wood, P. M., Pennica, D., Whittemore, S. R., and Tsoulfas, P. (2004). BMP signaling initiates a neural crest differentiation program in embryonic rat CNS stem cells . Exp Neurol 188 , 205-223.

Gang, E. J., Hong, S. H., Jeong, J. A., Hwang, S. H., Kim, S. W., Yang, I. H., Ahn, C., Han, H., and Kim, H. (2004). In vitro mesengenic potential of human umbilical cord blood-derived mesenchymal stem cells . Biochem Biophys Res Commun 321 , 102-108.

Hidalgo, A., Peired, A. J., Weiss, L. A., Katayama, Y., and Frenette, P. S. (2004). The integrin {alpha}M{beta}2 anchors hematopoietic progenitors in the bone marrow during enforced mobilization . Blood 104 , 993-1001.

Hitoshi, S., Seaberg, R. M., Koscik, C., Alexson, T., Kusunoki, S., Kanazawa, I., Tsuji, S., and van der Kooy, D. (2004). Primitive neural stem cells from the mammalian epiblast differentiate to definitive neural stem cells under the control of Notch signaling . Genes Dev 18 , 1806-1811.

Hochedlinger, K., Blelloch, R., Brennan, C., Yamada, Y., Kim, M., Chin, L., and Jaenisch, R. (2004). Reprogramming of a melanoma genome by nuclear transplantation . Genes Dev 18 , 1875-1885.

Horwitz, E. M. (2004). Dkk-1-mediated expansion of adult stem cells . Trends Biotechnol 22 , 386-388.

Jamieson, C. H., Ailles, L. E., Dylla, S. J., Muijtjens, M., Jones, C., Zehnder, J. L., Gotlib, J., Li, K., Manz, M. G., Keating, A. , et al. (2004). Granulocyte-macrophage progenitors as candidate leukemic stem cells in blast-crisis CML . N Engl J Med 351 , 657-667.

Jori, F. P., Napolitano, M. A., Melone, M. A., Cipollaro, M., Cascino, A., Giordano, A., and Galderisi, U. (2004). Role of RB and RB2/P130 genes in marrow stromal stem cells plasticity . J Cell Physiol 200 , 201-212.

Jung, C.-G., Hida, H., Nakahira, K., Ikenaka, K., Kim, H.-J., and Nishino, H. (2004). Pleiotrophin mRNA is highly expressed in neural stem (progenitor) cells of mouse ventral mesencephalon and the product promotes production of dopaminergic neurons from embryonic stem cell-derived nestin-positive cells . Faseb J 18 , 1237-1239.

Kang, S. K., Putnam, L. A., Ylostalo, J., Popescu, I. R., Dufour, J., Belousov, A., and Bunnell, B. A. (2004). Neurogenesis of Rhesus adipose stromal cells . J Cell Sci, jcs.01264.

Kelly, S., Bliss, T. M., Shah, A. K., Sun, G. H., Ma, M., Foo, W. C., Masel, J., Yenari, M. A., Weissman, I. L., Uchida, N. , et al. (2004). Transplanted human fetal neural stem cells survive, migrate, and differentiate in ischemic rat cerebral cortex . PNAS 101: , 11839-11844.

Kirito, K., Fox, N., and Kaushansky, K. (2004). Thrombopoietin Induces HOXA9 Nuclear Transport in Immature Hematopoietic Cells: Potential Mechanism by Which the Hormone Favorably Affects Hematopoietic Stem Cells . Mol Cell Biol 24 , 6751-6762.

Kobune, M., Ito, Y., Kawano, Y., Sasaki, K., Uchida, H., Nakamura, K., Dehari, H., Chiba, H., Takimoto, R., Matsunaga, T. , et al. (2004). Indian hedgehog gene transfer augments hematopoietic support of human stromal cells including NOD/SCID-{beta}2m-/- repopulating cells. Blood 104 , 1002-1009.

Kozar, K., Ciemerych, M. A., Rebel, V. I., Shigematsu, H., Zagozdzon, A., Sicinska, E., Geng, Y., Yu, Q., Bhattacharya, S., Bronson, R. T. , et al. (2004). Mouse development and cell proliferation in the absence of d-cyclins . Cell 118 , 477-491.

Maric, D., and Barker, J. L. (2004). Neural Stem Cells Redefined: A FACS Perspective . Mol Neurobiol 30 , 49-76.

Masino, A. M., Gallardo, T. D., Wilcox, C. A., Olson, E. N., Williams, R. S., and Garry, D. J. (2004). Transcriptional Regulation of Cardiac Progenitor Cell Populations . Circ Res 95 , 389-397.

Murakami, M., Ichisaka, T., Maeda, M., Oshiro, N., Hara, K., Edenhofer, F., Kiyama, H., Yonezawa, K., and Yamanaka, S. (2004). mTOR Is Essential for Growth and Proliferation in Early Mouse Embryos and Embryonic Stem Cells . Mol Cell Biol 24 , 6710-6718.

Otero, J. J., Fu, W., Kan, L., Cuadra, A. E., and Kessler, J. A. (2004). {beta}-Catenin signaling is required for neural differentiation of embryonic stem cells . Development 131 , 3545-3557.

Oustanina, S., Hause, G., and Braun, T. (2004). Pax7 directs postnatal renewal and propagation of myogenic satellite cells but not their specification . EMBO J 23 , 3430-3439.

Pan, G., Qin, B., Liu, N., Scholer, H. R., and Pei, D. (2004). Identification of a Nuclear Localization Signal in OCT4 and Generation of a Dominant Negative Mutant by Its Ablation . J Biol Chem 279 , 37013-37020.

Perrier, A. L., Tabar, V., Barberi, T., Rubio, M. E., Bruses, J., Topf, N., Harrison, N. L., and Studer, L. (2004). Derivation of midbrain dopamine neurons from human embryonic stem cells . PNAS 101 , 12543-12548.

Petersen, P. H., Zou, K., Krauss, S., and Zhong, W. (2004). Continuing role for mouse Numb and Numbl in maintaining progenitor cells during cortical neurogenesis . Nat Neurosci 7 , 803-811.

Plett, P. A., Abonour, R., Frankovitz, S. M., and Orschell, C. M. (2004). Impact of modeled microgravity on migration, differentiation, and cell cycle control of primitive human hematopoietic progenitor cells . Exp Hematol 32 , 773-781.

Raynaud, F., Carnac, G., Marcilhac, A., and Benyamin, Y. (2004). m-Calpain implication in cell cycle during muscle precursor cell activation . Exp Cell Res 298 , 48-57.

Staflin, K., Honeth, G., Kalliomaki, S., Kjellman, C., Edvardsen, K., and Lindvall, M. (2004). Neural Progenitor Cell Lines Inhibit Rat Tumor Growth in Vivo . Cancer Res 64 , 5347-5354.

Suzuki, A., Nakauchi, H., and Taniguchi, H. (2004). Prospective Isolation of Multipotent Pancreatic Progenitors Using Flow-Cytometric Cell Sorting . Diabetes 53 , 2143-2152.

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Zammit, P. S., Golding, J. P., Nagata, Y., Hudon, V., Partridge, T. A., and Beauchamp, J. R. (2004). Muscle satellite cells adopt divergent fates: a mechanism for self-renewal? J Cell Biol 166 , 347-357.

July 2004
Updated: January 04, 2005

Allegrucci, C., Denning, C., Priddle, H., and Young, L. (2004). Stem-cell consequences of embryo epigenetic defects . Lancet 364 , 206-208.

Almstrup, K., Hoei-Hansen, C. E., Wirkner, U., Blake, J., Schwager, C., Ansorge, W., Nielsen, J. E., Skakkebaek, N. E., Meyts, E. R.-D., and Leffers, H. (2004). Embryonic Stem Cell-Like Features of Testicular Carcinoma in Situ Revealed by Genome-Wide Gene Expression Profiling . Cancer Res 64 , 4736-4743.

Anderson, D. G., Levenberg, S., and Langer, R. (2004). Nanoliter-scale synthesis of arrayed biomaterials and application to human embryonic stem cells . Nat Biotechnol 22 , 863-866.

Arai, F., Hirao, A., Ohmura, M., Sato, H., Matsuoka, S., Takubo, K., Ito, K., Koh, G. Y., and Suda, T. (2004). Tie2/Angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche . Cell 118 , 149-161.

Campos, L. S., Leone, D. P., Relvas, J. B., Brakebusch, C., Fassler, R., Suter, U., and ffrench-Constant, C. (2004). {beta}1 integrins activate a MAPK signalling pathway in neural stem cells that contributes to their maintenance . Development 131 , 3433-3444.

Carr, A. R., Choksi, S. P., and Brand, A. H. (2004). Turning back the clock on neural progenitors . Bioessays 26 , 711-714.

Clayton, H., Titley, I., and Vivanco Md, M. (2004). Growth and differentiation of progenitor/stem cells derived from the human mammary gland . Exp Cell Res 297 , 444-460.

Dhara, S. K., and Benvenisty, N. (2004). Gene trap as a tool for genome annotation and analysis of X chromosome inactivation in human embryonic stem cells . Nucl Acids Res 32 , 3995-4002.

Frielingsdorf, H., Schwarz, K., Brundin, P., and Mohapel, P. (2004). No evidence for new dopaminergic neurons in the adult mammalian substantia nigra . Proc Natl Acad Sci U S A 101 , 10177-10182.

Garcion, E., Halilagic, A., Faissner, A., and ffrench-Constant, C. (2004). Generation of an environmental niche for neural stem cell development by the extracellular matrix molecule tenascin C . Development 131 , 3423-3432.

Georgantas, R. W., III, Tanadve, V., Malehorn, M., Heimfeld, S., Chen, C., Carr, L., Martinez-Murillo, F., Riggins, G., Kowalski, J., and Civin, C. I. (2004). Microarray and Serial Analysis of Gene Expression Analyses Identify Known and Novel Transcripts Overexpressed in Hematopoietic Stem Cells . Cancer Res 64 , 4434-4441.

Harder, F., Kirchhof, N., Petrovic, S., Wiese, S., and Muller, A. M. (2004). Erythroid-like cells from neural stem cells injected into blastocysts . Exp Hematol 32 , 673-682.

Hope, K. J., Jin, L., and Dick, J. E. (2004). Acute myeloid leukemia originates from a hierarchy of leukemic stem cell classes that differ in self-renewal capacity . Nat Immunol 5 , 738-743.

Humphrey, R. K., Beattie, G. M., Lopez, A. D., Bucay, N., King, C. C., Firpo, M. T., Rose-John, S., and Hayek, A. (2004). Maintenance of Pluripotency in Human Embryonic Stem Cells Is STAT3 Independent . Stem Cells 22 , 522-530.

Hussain, M. A., and Theise, N. D. (2004). Stem-cell therapy for diabetes mellitus . Lancet 364 , 203-205.

Joannides, A., Gaughwin, P., Schwiening, C., Majed, H., Sterling, J., Compston, P. A., and Chandran, S. (2004). Efficient generation of neural precursors from adult human skin: astrocytes promote neurogenesis from skin-derived stem cells . Lancet 364 , 172-178.

Khosrotehrani, K., Johnson, K. L., Cha, D. H., Salomon, R. N., and Bianchi, D. W. (2004). Transfer of Fetal Cells With Multilineage Potential to Maternal Tissue . JAMA 292 , 75-80.

Kogler, G., Sensken, S., Airey, J. A., Trapp, T., Muschen, M., Feldhahn, N., Liedtke, S., Sorg, R. V., Fischer, J., Rosenbaum, C. , et al. (2004). A New Human Somatic Stem Cell from Placental Cord Blood with Intrinsic Pluripotent Differentiation Potential . J Exp Med 200 , 123-135.

Lakshmipathy, U., Pelacho, B., Sudo, K., Linehan, J. L., Coucouvanis, E., Kaufman, D. S., and Verfaillie, C. M. (2004). Efficient Transfection of Embryonic and Adult Stem Cells . Stem Cells 22 , 531-543.

Leon-Quinto, T., Jones, J., Skoudy, A., Burcin, M., and Soria, B. (2004). In vitro directed differentiation of mouse embryonic stem cells into insulin-producing cells . Diabetologia 47 , 1442-1451.

Li, H., Corrales, C. E., Edge, A., and Heller, S. (2004a). Stem cells as therapy for hearing loss . Trends Mol Med 10 , 309-315.

Li, L., Baroja, M. L., Majumdar, A., Chadwick, K., Rouleau, A., Gallacher, L., Ferber, I., Lebkowski, J., Martin, T., Madrenas, J., and Bhatia, M. (2004b). Human Embryonic Stem Cells Possess Immune-Privileged Properties . Stem Cells 22 , 448-456.

Mathur, A., and Martin, P. J. (2004). Stem cells and repair of the heart . Lancet 364 , 183-192.

Mattsson, J., Jansson, M., Wernerson, A., and Hassan, M. (2004). Lung Epithelial Cells and Type II Pneumocytes of Donor Origin After Allogeneic Hematopoietic Stem Cell Transplantation . Transplantation 78 , 154-157.

McBride, J. L., Behrstock, S. P., Chen, E. Y., Jakel, R. J., Siegel, I., Svendsen, C. N., and Kordower, J. H. (2004). Human neural stem cell transplants improve motor function in a rat model of Huntington's disease . J Comp Neurol 475 , 211-219.

Miranville, A., Heeschen, C., Sengenes, C., Curat, C. A., Busse, R., and Bouloumie, A. (2004). Improvement of Postnatal Neovascularization by Human Adipose Tissue-Derived Stem Cells . Circulation 110 , 349-355.

Miyamoto, K., Hayashi, K., Suzuki, T., Ichihara, S., Yamada, T., Kano, Y., Yamabe, T., and Ito, Y. (2004). Human Placenta Feeder Layers Support Undifferentiated Growth of Primate Embryonic Stem Cells . Stem Cells 22 , 433-440.

Morigi, M., Imberti, B., Zoja, C., Corna, D., Tomasoni, S., Abbate, M., Rottoli, D., Angioletti, S., Benigni, A., Perico, N. , et al. (2004). Mesenchymal stem cells are renotropic, helping to repair the kidney and improve function in acute renal failure . J Am Soc Nephrol 15 , 1794-1804.

Nayernia, K., Li, M., Jaroszynski, L., Khusainov, R., Wulf, G., Schwandt, I., Korabiowska, M., Michelmann, H. W., Meinhardt, A., and Engel, W. (2004). Stem cell-based therapeutical approach of male infertility by teratocarcinoma derived germ cells . Hum Mol Genet 13 , 1451-1460.

O'Donoghue, K., Chan, J., De La Fuente, J., Kennea, N., Sandison, A., Anderson, J. R., Roberts, P. I., and Fisk, P. N. (2004). Microchimerism in female bone marrow and bone decades after fetal mesenchymal stem-cell trafficking in pregnancy . Lancet 364 , 179-182.

Ohkubo, Y., Uchida, A. O., Shin, D., Partanen, J., and Vaccarino, F. M. (2004). Fibroblast growth factor receptor 1 is required for the proliferation of hippocampal progenitor cells and for hippocampal growth in mouse . J Neurosci 24 , 6057-6069.

Peng, Y., Kang, Q., Luo, Q., Jiang, W., Si, W., Liu, B. A., Luu, H. H., Park, J. K., Li, X., Luo, J. , et al. (2004a). Id Helix-loop-helix proteins mediate BMP-induced osteoblast differentiation of mesenchymal stem cells . J Biol Chem 279 , 32941-32949.

Peng, Y., Kang, Q., Luo, Q., Jiang, W., Si, W., Liu, B. A., Luu, H. H., Park, J. K., Li, X., Luo, J. , et al. (2004b). Inhibitor of DNA Binding/Differentiation Helix-Loop-Helix Proteins Mediate Bone Morphogenetic Protein-induced Osteoblast Differentiation of Mesenchymal Stem Cells . J Biol Chem 279 , 32941-32949.

Rice, C. M., and Scolding, P. N. (2004). Adult stem cells-reprogramming neurological repair? Lancet 364 , 193-199.

Richardson, G. D., Robson, C. N., Lang, S. H., Neal, D. E., Maitland, N. J., and Collins, A. T. (2004). CD133, a novel marker for human prostatic epithelial stem cells . J Cell Sci 117 , 3539-3545.

Seo, B. M., Miura, M., Gronthos, S., Bartold, P. P., Batouli, S., Brahim, J., Young, M., Robey, P. G., Wang, P. C., and Shi, S. (2004). Investigation of multipotent postnatal stem cells from human periodontal ligament . Lancet 364 , 149-155.

Silani, P. V., Cova, L., Corbo, M., Ciammola, A., and Prof Polli, E. (2004). Stem-cell therapy for amyotrophic lateral sclerosis . Lancet 364 , 200-202.

Taylor, H. S. (2004). Endometrial Cells Derived From Donor Stem Cells in Bone Marrow Transplant Recipients . JAMA 292 , 81-85.

Torrente, Y., Belicchi, M., Sampaolesi, M., Pisati, F., Meregalli, M., D'Antona, G., Tonlorenzi, R., Porretti, L., Gavina, M., Mamchaoui, K. , et al. (2004). Human circulating AC133+ stem cells restore dystrophin expression and ameliorate function in dystrophic skeletal muscle . J Clin Invest 114 , 182-195.

Urbach, A., Schuldiner, M., and Benvenisty, N. (2004). Modeling for Lesch-Nyhan Disease by Gene Targeting in Human Embryonic Stem Cells . Stem Cells 22 , 635-641.

Wandzioch, E., Edling, C. E., Palmer, R. H., Carlsson, L., and Hallberg, B. (2004). Activation of the MAP kinase pathway by c-Kit is PI-3 kinase dependent in hematopoietic progenitor/stem cell lines . Blood 104 , 51-57.

Wang, L., Li, L., Shojaei, F., Levac, K., Cerdan, C., Menendez, P., Martin, T., Rouleau, A., and M., B. (2004). Endothelial and Hematopoietic Cell Fate of Human Embryonic Stem Cells Originates from Primitive Endothelium with Hemangioblastic Properties . Immunity 21 , 31-41.

Willenbring, H., Bailey, A. S., Foster, M., Akkari, Y., Dorrell, C., Olson, S., Finegold, M., Fleming, W. H., and Grompe, M. (2004). Myelomonocytic cells are sufficient for therapeutic cell fusion in liver . Nat Med 10 , 744-748.

Wollert, K. C., Meyer, G. P., Lotz, J., Ringes-Lichtenberg, S., Lippolt, P., Breidenbach, C., Fichtner, S., Korte, T., Hornig, B., Messinger, D. , et al. (2004). Intracoronary autologous bone-marrow cell transfer after myocardial infarction: the BOOST randomised controlled clinical trial . Lancet 364 , 141-148.

Wurmser, A. E., Nakashima, K., Summers, R. G., Toni, N., D'Amour, K. A., Lie, D. C., and Gage, F. H. (2004). Cell fusion-independent differentiation of neural stem cells to the endothelial lineage . Nature 430 , 350-356.

Xian, H., and Gottlieb, D. I. (2004). Dividing Olig2-expressing progenitor cells derived from ES cells . Glia 47 , 88-101.

Xu, L., O'Malley, T., Sands, M. S., Wang, B., Meyerrose, T., Haskins, M. E., and Ponder, K. P. (2004). In vivo transduction of hematopoietic stem cells after neonatal intravenous injection of an amphotropic retroviral vector in mice . Mol Ther 10 , 37-44.

Zhan, X., Dravid, G., Ye, Z., Hammond, H., Shamblott, M., Gearhart, J., and Cheng, L. (2004). Functional antigen-presenting leucocytes derived from human embryonic stem cells in vitro . Lancet 364 , 163-171.

Zhang, W. J., Park, C., Arentson, E., and Choi, K. (2004). Modulation of hematopoietic and endothelial cell differentiation from mouse embryonic stem cells by different culture conditions . Blood, 2004-2004-1306.

June 2004
Updated: January 04, 2005

Baharvand, H., Ashtiani, S. K., Valojerdi, M. R., Shahverdi, A., Taee, A., and Sabour, D. (2004). Establishment and in vitro differentiation of a new embryonic stem cell line from human blastocyst . Differentiation 72 , 224-229.

Brandenberger, R., Wei, H., Zhang, S., Lei, S., Murage, J., Fisk, G. J., Li, Y., Xu, C., Fang, R., Guegler, K. , et al. (2004). Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation . Nat Biotechnol 22 , 707-716.

Brun, A. C., Bjornsson, J. M., Magnusson, M., Larsson, N., Leveen, P., Ehinger, M., Nilsson, E., and Karlsson, S. (2004). Hoxb4 deficient mice have normal hematopoietic development but exhibit a mild proliferation defect in hematopoietic stem cells . Blood 103 , 4126-4133.

Brunelli, S., Tagliafico, E., De Angelis, F. G., Tonlorenzi, R., Baesso, S., Ferrari, S., Niinobe, M., Yoshikawa, K., Schwartz, R. J., Bozzoni, I. , et al. (2004). Msx2 and Necdin Combined Activities Are Required for Smooth Muscle Differentiation in Mesoangioblast Stem Cells . Circ Res 94 , 1571-1578.

Buaas, F. W., Kirsh, A. L., Sharma, M., McLean, D. J., Morris, J. L., Griswold, M. D., de Rooij, D. G., and Braun, R. E. (2004). Plzf is required in adult male germ cells for stem cell self-renewal . Nat Genet 36 , 647-652.

Costoya, J. A., Hobbs, R. M., Barna, M., Cattoretti, G., Manova, K., Sukhwani, M., Orwig, K. E., Wolgemuth, D. J., and Pandolfi, P. P. (2004). Essential role of Plzf in maintenance of spermatogonial stem cells . Nat Genet 36 , 653-659.

Dezawa, M., Kanno, H., Hoshino, M., Cho, H., Matsumoto, N., Itokazu, Y., Tajima, N., Yamada, H., Sawada, H., Ishikawa, H. , et al. (2004). Specific induction of neuronal cells from bone marrow stromal cells and application for autologous transplantation . J Clin Invest 113 , 1701-1710.

D'Ippolito, G., Diabira, S., Howard, G. A., Menei, P., Roos, B. A., and Schiller, P. C. (2004). Marrow-isolated adult multilineage inducible (MIAMI) cells, a unique population of postnatal young and old human cells with extensive expansion and differentiation potential . J Cell Sci 117 , 2971-2981.

Gammaitoni, L., Weisel, K. C., Gunetti, M., Wu, K.-D., Bruno, S., Pinelli, S., Bonati, A., Aglietta, M., Moore, M. A., and Piacibello, W. (2004). Elevated telomerase activity, minimal telomere loss in cord blood long-term cultures with extensive stem cell replication . Blood 103 , 4440-4448.

Gilboa, L., and Lehmann, R. (2004). Repression of primordial germ cell differentiation parallels germ line stem cell maintenance . Curr Biol 14 , 981-986.

Gurok, U., Steinhoff, C., Lipkowitz, B., Ropers, H. H., Scharff, C., and Nuber, U. A. (2004). Gene expression changes in the course of neural progenitor cell differentiation . J Neurosci 24 , 5982-6002.

Hanawa, H., Hematti, P., Keyvanfar, K., Metzger, M. E., Krouse, A., Donahue, R. E., Kepes, S., Gray, J., Dunbar, C. E., Persons, D. A., and Nienhuis, A. W. (2004). Efficient gene transfer into rhesus repopulating hematopoietic stem cells using a simian immunodeficiency virus-based lentiviral vector system . Blood 103 , 4062-4069.

Horiuchi, H., Tategaki, A., Yamashita, Y., Hisamatsu, H., Ogawa, M., Noguchi, T., Aosasa, M., Kawashima, T., Akita, S., Nishimichi, N. , et al. (2004). Chicken leukemia inhibitory factor maintains chicken embryonic stem cells in the undifferentiated state . J Biol Chem 279 , 24514-24520.

Inzunza, J., Sahlen, S., Holmberg, K., Stromberg, A.-M., Teerijoki, H., Blennow, E., Hovatta, O., and Malmgren, H. (2004). Comparative genomic hybridization and karyotyping of human embryonic stem cells reveals the occurrence of an isodicentric X chromosome after long-term cultivation . Mol Hum Reprod 10 , 461-466.

Jang, Y. Y., Collector, M. I., Baylin, S. B., Diehl, A. M., and Sharkis, S. J. (2004). Hematopoietic stem cells convert into liver cells within days without fusion . Nat Cell Biol 6 , 532-539.

Kajiume, T., Ninomiya, Y., Ishihara, H., Kanno, R., and Kanno, M. (2004). Polycomb group gene mel-18 modulates the self-renewal activity and cell cycle status of hematopoietic stem cells . Exp Hematol 32 , 571-578.

Lavon, N., Yanuka, O., and Benvenisty, N. (2004). Differentiation and isolation of hepatic-like cells from human embryonic stem cells . Differentiation 72 , 230-238.

Levesque, J. P., Liu, F., Simmons, P. J., Betsuyaku, T., Senior, R., Pham, C., and Link, D. C. (2004). Characterization of Hematopoietic Progenitor Mobilization in Protease Deficient Mice . Blood 104 , 65-72.

Lopez-Toledano, M. A., and Shelanski, M. L. (2004). Neurogenic Effect of {beta}-Amyloid Peptide in the Development of Neural Stem Cells . J Neurosci 24 , 5439-5444.

Lu, S.-J., Li, F., Vida, L., and Honig, G. R. (2004). CD34+CD38- hematopoietic precursors derived from human embryonic stem cells exhibit an embryonic gene expression pattern . Blood 103 , 4134-4141.

Milhem, M., Mahmud, N., Lavelle, D., Araki, H., DeSimone, J., Saunthararajah, Y., and Hoffman, R. (2004). Modification of hematopoietic stem cell fate by 5aza 2'deoxycytidine and trichostatin A . Blood 103 , 4102-4110.

Muller-Sieburg, C. E., Cho, R. H., Karlsson, L., Huang, J.-F., and Sieburg, H. B. (2004). Myeloid-biased hematopoietic stem cells have extensive self-renewal capacity but generate diminished lymphoid progeny with impaired IL-7 responsiveness . Blood 103 , 4111-4118.

Nakajima-Nagata, N., Sakurai, T., Mitaka, T., Katakai, T., Yamato, E., Miyazaki, J., Tabata, Y., Sugai, M., and Shimizu, A. (2004). In vitro induction of adult hepatic progenitor cells into insulin-producing cells . Biochem Biophys Res Commun 318 , 625-630.

Notingher, I., Bisson, I., Bishop, A. E., Randle, W. L., Polak, J. M., and Hench, L. L. (2004). In situ spectral monitoring of mRNA translation in embryonic stem cells during differentiation in vitro . Anal Chem 76 , 3185-3193.

Okubo, T., and Hogan, B. (2004). Hyperactive Wnt signaling changes the developmental potential of embryonic lung endoderm . Journal of Biology 3 , 11.

Orelio, C., Harvey, K. N., Miles, C., Oostendorp, R. A. J., van der Horn, K., and Dzierzak, E. (2004). The role of apoptosis in the development of AGM hematopoietic stem cells revealed by Bcl-2 overexpression . Blood 103 , 4084-4092.

Park, C., Afrikanova, I., Chung, Y. S., Zhang, W. J., Arentson, E., Fong, G. h., Rosendahl, A., and Choi, K. (2004). A hierarchical order of factors in the generation of FLK1- and SCL-expressing hematopoietic and endothelial progenitors from embryonic stem cells . Development 131 , 2749-2762.

Pochampally, R. R., Neville, B. T., Schwarz, E. J., Li, M. M., and Prockop, D. J. (2004). Rat adult stem cells (marrow stromal cells) engraft and differentiate in chick embryos without evidence of cell fusion . PNAS 101 , 9282-9285.

Satoh, Y., Matsumura, I., Tanaka, H., Ezoe, S., Sugahara, H., Mizuki, M., Shibayama, H., Ishiko, E., Ishiko, J., Nakajima, K., and Kanakura, Y. (2004). Roles for c-Myc in Self-renewal of Hematopoietic Stem Cells . J Biol Chem 279 , 24986-24993.

Schomber, T., Kalberer, C. P., Wodnar-Filipowicz, A., and Skoda, R. C. (2004). Gene silencing by lentivirus-mediated delivery of siRNA in human CD34+ cells . Blood 103 , 4511-4513.

Shi, D., Reinecke, H., Murry, C. E., and Torok-Storb, B. (2004). Myogenic fusion of human bone marrow stromal cells, but not hematopoietic cells . Blood 104 , 290-294.

Shin, M. G., Kajigaya, S., Tarnowka, M., McCoy, J. P., Levin, B. C., and Young, N. S. (2004). Mitochondrial DNA sequence heterogeneity in circulating normal human CD34 cells and granulocytes . Blood 103 , 4466-4477.

Simard, A. R., and Rivest, S. (2004). Bone marrow stem cells have the ability to populate the entire central nervous system into fully differentiated parenchymal microglia . FASEB J 18 , 998-1000.

Song, L., and Tuan, R. S. (2004). Transdifferentiation potential of human mesenchymal stem cells derived from bone marrow . Faseb J 18 , 980-982.

Strick-Marchand, H., Morosan, S., Charneau, P., Kremsdorf, D., and Weiss, M. C. (2004). Bipotential mouse embryonic liver stem cell lines contribute to liver regeneration and differentiate as bile ducts and hepatocytes . PNAS 101 , 8360-8365.

Suh, M. R., Lee, Y., Kim, J. Y., Kim, S. K., Moon, S. H., Lee, J. Y., Cha, K. Y., Chung, H. M., Yoon, H. S., Moon, S. Y. , et al. (2004). Human embryonic stem cells express a unique set of microRNAs . Dev Biol 270 , 488-498.

Tsai, M.-S., Lee, J.-L., Chang, Y.-J., and Hwang, S.-M. (2004). Isolation of human multipotent mesenchymal stem cells from second-trimester amniotic fluid using a novel two-stage culture protocol . Hum Reprod 19 , 1450-1456.

Uchida, N., Dykstra, B., Lyons, K., Leung, F., Kristiansen, M., and Eaves, C. (2004). ABC transporter activities of murine hematopoietic stem cells vary according to their developmental and activation status . Blood 103 , 4487-4495.

Yoon, Y.-S., Park, J.-S., Tkebuchava, T., Luedeman, C., and Losordo, D. W. (2004). Unexpected Severe Calcification After Transplantation of Bone Marrow Cells in Acute Myocardial Infarction . Circulation 109 , 3154-3157.

May 2004
Updated: January 04, 2005

Abdallah, B. M., Jensen, C. H., Gutierrez, G., Leslie, R. G., Jensen, T. G., and Kassem, M. (2004). Regulation of Human Skeletal Stem Cells Differentiation by Dlk1/Pref-1 . J Bone Miner Res 19 , 841-852.

Bensidhoum, M., Chapel, A., Francois, S., Demarquay, C., Mazurier, C., Fouillard, L., Bouchet, S., Bertho, J. M., Gourmelon, P., Aigueperse, J. , et al. (2004). Homing of in vitro expanded Stro-1- or Stro-1+ human mesenchymal stem cells into the nod/scid mouse. Their role in supporting human CD34 cell engraftment . Blood 103 , 3313-3319.

Bourne, S., Polak, J. M., Hughes, S. P., and Buttery, L. D. (2004). Osteogenic differentiation of mouse embryonic stem cells: differential gene expression analysis by cDNA microarray and purification of osteoblasts by cadherin-11 magnetically activated cell sorting . Tissue Eng 10 , 796-806.

Brawley, C., and Matunis, E. (2004). Regeneration of Male Germline Stem Cells by Spermatogonial Dedifferentiation in Vivo . Science 304 , 1331-1334.

Bryja, V., Pachernik, J., Soucek, K., Horvath, V., Dvorak, P., and Hampl, A. (2004). Increased apoptosis in differentiating p27-deficient mouse embryonic stem cells . Cell Mol Life Sci 61 , 1384-1400.

Caille, I., Allinquant, B., Dupont, E., Bouillot, C., Langer, A., Muller, U., and Prochiantz, A. (2004). Soluble form of amyloid precursor protein regulates proliferation of progenitors in the adult subventricular zone . Development 131 , 2173-2181.

Camargo, F. D., Finegold, M., and Goodell, M. A. (2004). Hematopoietic myelomonocytic cells are the major source of hepatocyte fusion partners . J Clin Invest 113 , 1266-1270.

Casanueva, M. O., and Ferguson, E. L. (2004). Germline stem cell number in the Drosophila ovary is regulated by redundant mechanisms that control Dpp signaling . Development 131 , 1881-1890.

Chambeyron, S., and Bickmore, W. A. (2004). Chromatin decondensation and nuclear reorganization of the HoxB locus upon induction of transcription . Genes Dev 18 , 1119-1130.

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