Stem Cell Science Literature

December 2003
Updated: April 28, 2004

Aarum, J., Sandberg, K., Haeberlein, S. L., and Persson, M. A. (2003). Migration and differentiation of neural precursor cells can be directed by microglia . Proc Natl Acad Sci U S A 100, 15983-15988.

Barros, C. S., Phelps, C. B., and Brand, A. H. (2003). Drosophila nonmuscle myosin II promotes the asymmetric segregation of cell fate determinants by cortical exclusion rather than active transport . Dev Cell 5, 829-840.

Bejar, J., Hong, Y., and Schartl, M. (2003). Mitf expression is sufficient to direct differentiation of medaka blastula derived stem cells to melanocytes . Development 130, 6545-6553.

Camargo, F. D., Green, R., Capetenaki, Y., Jackson, K. A., and Goodell, M. A. (2003). Single hematopoietic stem cells generate skeletal muscle through myeloid intermediates . Nat Med 9, 1520 - 1527.

Chandran, S., Kato, H., Gerreli, D., Compston, A., Svendsen, C. N., and Allen, N. D. (2003). FGF-dependent generation of oligodendrocytes by a hedgehog-independent pathway . Development 130, 6599-6609.

Chapel, A., Bertho, J., Bensidhoum, M., Fouillard, L., Young, R., Frick, J., Demarquay, C., Cuvelier, F., Mathieu, E., Trompier, F. , et al. (2003). Mesenchymal stem cells home to injured tissues when co-infused with hematopoietic cells to treat a radiation-induced multi-organ failure syndrome. J Gene Med 5, 1028-1038.

Chen, Y., Ke, Q., Yang, Y., Rana, J. S., Tang, J., Morgan, J. P., and Xiao, Y. F. (2003). Cardiomyocytes overexpressing TNF-{alpha} attract migration of embryonic stem cells via activation of p38 and c-Jun amino-terminal kinase . Faseb J 17, 2231-2239.

Corbel, S. Y., Lee, A., Yi, L., Duenas, J., Brazelton, T. R., Blau, H. M., and Rossi, F. M. (2003). Contribution of hematopoietic stem cells to skeletal muscle . Nat Med 9, 1528 - 1532.

Dahlqvist, C., Blokzijl, A., Chapman, G., Falk, A., Dannaeus, K., Ibanez, C. F., and Lendahl, U. (2003). Functional Notch signaling is required for BMP4-induced inhibition of myogenic differentiation . Development 130, 6089-6099.

Driessen, R. L., Johnston, H. M., and Nilsson, S. K. (2003). Membrane-bound stem cell factor is a key regulator in the initial lodgment of stem cells within the endosteal marrow region . Exp Hematol 31, 1284-1291.

Easterday, M. C., Dougherty, J. D., Jackson, R. L., Ou, J., Nakano, I., Paucar, A. A., Roobini, B., Dianati, M., Irvin, D. K., Weissman, I. L. , et al. (2003). Neural progenitor genes. Germinal zone expression and analysis of genetic overlap in stem cell populations . Dev Biol 264, 309-322.

Eggan, K., and Jaenisch, R. (2003). Differentiation of F1 embryonic stem cells into viable male and female mice by tetraploid embryo complementation . Methods Enzymol 365, 25-39.

Furuya, M., Yasuchika, K., Mizutani, K., Yoshimura, Y., Nakatsuji, N., and Suemori, H. (2003). Electroporation of cynomolgus monkey embryonic stem cells . Genesis 37, 180-187.

Gambardella, L., and Barrandon, Y. (2003). The multifaceted adult epidermal stem cell . Curr Opin Cell Biol 15, 771-777.

Gao, C., Kang, E. M., Kuramoto, K., Agricola, B. A., Metzger, M., von Kalle, C., Donahue, R. E., and Tisdale, J. F. (2003). Retrovirally transduced muscle-derived cells contribute to hematopoiesis at very low levels in the nonhuman primate model . Mol Ther 8, 974-980.

Gilboa, L., Forbes, A., Tazuke, S. I., Fuller, M. T., and Lehmann, R. (2003). Germ line stem cell differentiation in Drosophila requires gap junctions and proceeds via an intermediate state . Development 130, 6625-6634.

Goolsby, J., Marty, M. C., Heletz, D., Chiappelli, J., Tashko, G., Yarnell, D., Fishman, P. S., Dhib-Jalbut, S., Bever, C. T., Jr., Pessac, B., and Trisler, D. (2003). Hematopoietic progenitors express neural genes . PNAS 100, 14926-14931.

Green, H., Easley, K., and Iuchi, S. (2003). Marker succession during the development of keratinocytes from cultured human embryonic stem cells . PNAS 100, 15625-15630.

Gregg, C., and Weiss, S. (2003). Generation of functional radial glial cells by embryonic and adult forebrain neural stem cells . J Neurosci 23, 11587-11601.

Hasumura, M., Imada, C., and Nawa, K. (2003). Expression change of Flk-2/Flt-3 on murine hematopoietic stem cells in an activating state . Exp Hematol 31, 1331-1337.

Hirano, M., Yamamoto, A., Yoshimura, N., Tokunaga, T., Motohashi, T., Ishizaki, K., Yoshida, H., Okazaki, K., Yamazaki, H., Hayashi, S., and Kunisada, T. (2003). Generation of structures formed by lens and retinal cells differentiating from embryonic stem cells . Dev Dyn 228, 664-671.

Horn, P. A., Thomasson, B. M., Wood, B. L., Andrews, R. G., Morris, J. C., and Kiem, H. P. (2003). Distinct hematopoietic stem/progenitor cell populations are responsible for repopulating NOD/SCID mice versus nonhuman primates . Blood 102, 4329-4335.

Hussein, S. M., Duff, E. K., and Sirard, C. (2003). Smad4 and beta -catenin coactivators functionally interact with LEF1 to regulate graded expression of Msx2 . J Biol Chem 278, 48805-48814.

Kruger, G. M., Mosher, J. T., Tsai, Y. H., Yeager, K. J., Iwashita, T., Gariepy, C. E., and Morrison, S. J. (2003). Temporally distinct requirements for endothelin receptor B in the generation and migration of gut neural crest stem cells . Neuron 40, 917-929.

Legg, J., Jensen, U. B., Broad, S., Leigh, I., and Watt, F. M. (2003). Role of melanoma chondroitin sulphate proteoglycan in patterning stem cells in human interfollicular epidermis . Development 130, 6049-6063.

Levasseur, D. N., Ryan, T. M., Pawlik, K. M., and Townes, T. M. (2003). Correction of a mouse model of sickle cell disease: lentiviral/anti-sickling {beta}-globin gene transduction of unmobilized, purified hematopoietic stem cells . Blood 102, 4312-4319.

Li, L., and Akashi, K. (2003). Unraveling the molecular components and genetic blueprints of stem cells . Biotechniques 35, 1233-1239.

 Li, W., Johnson, S. A., Shelley, W. C., Ferkowicz, M., Morrison, P., Li, Y., and Yoder, M. C. (2003b). Primary endothelial cells isolated from the yolk sac and para-aortic splanchnopleura support the expansion of adult marrow stem cells in vitro . Blood 102, 4345-4353.

Loebel, D. A., Watson, C. M., De Young, R. A., and Tam, P. P. (2003). Lineage choice and differentiation in mouse embryos and embryonic stem cells . Dev Biol 264, 1-14.

Meng, A., Wang, Y., Brown, S. A., Van Zant, G., and Zhou, D. (2003). Ionizing radiation and busulfan inhibit murine bone marrow cell hematopoietic function via apoptosisdependent and -independent mechanisms . Exp Hematol 31, 1348-1356.

Miura, T., Ohota, T., Miura, C. I., and Yamauchi, K. (2003). Complementary deoxyribonucleic acid cloning of spermatogonial stem-cell renewal factor . Endocrinology 144, 5504-5510.

Muguruma, Y., Reyes, M., Nakamura, Y., Sato, T., Matsuzawa, H., Miyatake, H., Akatsuka, A., Itoh, J., Yahata, T., Ando, K. , et al. (2003). In vivo and in vitro differentiation of myocytes from human bone marrow-derived multipotentprogenitor cells . Exp Hematol 31, 1323-1330.

Nobuhisa, I., Takizawa, M., Takaki, S., Inoue, H., Okita, K., Ueno, M., Takatsu, K., and Taga, T. (2003). Regulation of hematopoietic development in the aorta-gonad-mesonephros region mediated by lnk adaptor protein . Mol Cell Biol 23, 8486-8494.

Norol, F., Merlet, P., Isnard, R., Sebillon, P., Bonnet, N., Cailliot, C., Carrion, C., Ribeiro, M., Charlotte, F., Pradeau, P. , et al. (2003). Influence of mobilized stem cells on myocardial infarct repair in a nonhuman primate model . Blood 102, 4361-4368.

Olmsted-Davis, E. A., Gugala, Z., Camargo, F., Gannon, F. H., Jackson, K., Kienstra, K. A., Shine, H. D., Lindsey, R. W., Hirschi, K. K., Goodell, M. A. , et al. (2003). Primitive adult hematopoietic stem cells can function as osteoblast precursors . Proc Natl Acad Sci U S A 100, 15877-15882.

Pan, G. J., and Pei, D. Q. (2003). Identification of two distinct transactivation domains in the pluripotency sustaining factor nanog . Cell Res 13, 499-502.

Pera, M. F., Filipczyk, A. A., Hawes, S. M., and Laslett, A. L. (2003). Isolation, characterization, and differentiation of human embryonic stem cells . Methods Enzymol 365, 429-446.

Sancho, E., Batlle, E., and Clevers, H. (2003). Live and let die in the intestinal epithelium . Curr Opin Cell Biol 15, 763-770.

Sharov, A. A., Piao, Y., Matoba, R., Dudekula, D. B., Qian, Y., VanBuren, V., Falco, G., Martin, P. R., Stagg, C. A., Bassey, U. C. , et al. (2003). Transcriptome Analysis of Mouse Stem Cells and Early Embryos . PLoS Biol 1, E74.

Shivdasani, A. A., and Ingham, P. W. (2003). Regulation of Stem Cell Maintenance and Transit Amplifying Cell Proliferation by TGF-beta Signaling in Drosophila Spermatogenesis . Curr Biol 13, 2065-2072.

Smulders-Srinivasan, T. K., and Lin, H. (2003). Screens for piwi Suppressors in Drosophila Identify Dosage-Dependent Regulators of Germline Stem Cell Division . Genetics 165, 1971-1991.

Traver, D., Paw, B. H., Poss, K. D., Penberthy, W. T., Lin, S., and Zon, L. I. (2003). Transplantation and in vivo imaging of multilineage engraftment in zebrafish bloodless mutants . Nat Immunol 4, 1238-1246.

Uchida, N., Dykstra, B., Lyons, K. J., Leung, F. Y., and Eaves, C. J. (2003). Different in vivo repopulating activities of purified hematopoietic stem cells before and after being stimulated to divide in vitro with the same kinetics . Exp Hematol 31, 1338-1347.

Ueki, T., Tanaka, M., Yamashita, K., Mikawa, S., Qiu, Z., Maragakis, N. J., Hevner, R. F., Miura, N., Sugimura, H., and Sato, K. (2003). A novel secretory factor, Neurogenesin-1, provides neurogenic environmental cues for neural stem cells in the adult hippocampus . J Neurosci 23, 11732-11740.

Viswanathan, S., Benatar, T., Mileikovsky, M., Lauffenburger, D. A., Nagy, A., and Zandstra, P. W. (2003). Supplementation-dependent differences in the rates of embryonic stem cell self-renewal, differentiation, and apoptosis . Biotechnol Bioeng 84, 505-517.

Watabe, T., Nishihara, A., Mishima, K., Yamashita, J., Shimizu, K., Miyazawa, K., Nishikawa, S.-I., and Miyazono, K. (2003). TGF-{beta} receptor kinase inhibitor enhances growth and integrity of embryonic stem cell-derived endothelial cells . J Cell Biol 163, 1303-1311.

Xiao, C., Shim, J. H., Kluppel, M., Zhang, S. S., Dong, C., Flavell, R. A., Fu, X. Y., Wrana, J. L., Hogan, B. L., and Ghosh, S. (2003). Ecsit is required for Bmp signaling and mesoderm formation during mouse embryogenesis . Genes Dev 17, 2933-2949.



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November 2003
Updated: March 23, 2004

Blokzijl, A., Dahlqvist, C., Reissmann, E., Falk, A., Moliner, A., Lendahl, U., and Ibanez, C. F. (2003). Cross-talk between the Notch and TGF-{beta} signaling pathways mediated by interaction of the Notch intracellular domain with Smad3. J Cell Biol 163, 723-728.

Chang, S. C., Chuang, H. L., Chen, Y. R., Chen, J. K., Chung, H. Y., Lu, Y. L., Lin, H. Y., Tai, C. L., and Lou, J. (2003). Ex vivo gene therapy in autologous bone marrow stromal stem cells for tissue-engineered maxillofacial bone regeneration. Gene Ther 10, 2013-2019.

da Silva Meireelles, L., and Nardi, N. B. (2003). Murine marrow-derived mesenchymal stem cell: isolation, in vitro expansion, and characterization. Br J Haematol 123, 702-711.

Haegele, L., Ingold, B., Naumann, H., Tabatabai, G., Ledermann, B., and Brandner, S. (2003). Wnt signalling inhibits neural differentiation of embryonic stem cells by controlling bone morphogenetic protein expression. Mol Cell Neurosci 24, 696-708.

Hartner, J. C., Schmittwolf, C., Kispert, A., Mueller, A. M., Higuchi, M., and Seeburg, P. H. (2003). Liver disintegration in the mouse embryo by deficiency in RNA editing enzyme ADAR1. J Biol Chem, M311347200.

Heilig, C., Brosius, F., Siu, B., Concepcion, L., Mortensen, R., Heilig, K., Zhu, M., Weldon, R., Wu, G., and Conner, D. (2003). Implications of Glucose Transporter Protein Type 1 (GLUT1)-Haplodeficiency in Embryonic Stem Cells for Their Survival in Response to Hypoxic Stress. Am J Pathol 163, 1873-1885.

Helgason, C. D., Antonchuk, J., Bodner, C., and Humphries, R. K. (2003). Homeostasis and regeneration of the hematopoietic stem cell pool are altered in SHIP-deficient mice. Blood 102, 3541-3547.

Ishizuka, S., Martin, K., Booth, C., Potten, C. S., de Murcia, G., Burkle, A., and Kirkwood, T. B. L. (2003). Poly(ADP-ribose) polymerase-1 is a survival factor for radiation-exposed intestinal epithelial stem cells in vivo. Nucl Acids Res 31, 6198-6205.

Kim, M., and Morshead, C. M. (2003). Distinct Populations of Forebrain Neural Stem and Progenitor Cells Can Be Isolated Using Side-Population Analysis. J Neurosci 23, 10703-10709.

Kyba, M., and Daley, G. Q. (2003). Hematopoiesis from embryonic stem cells: lessons from and for ontogeny. Exp Hematol 31, 994-1006.

Larsson, J., Blank, U., Helgadottir, H., Bjornsson, J. M., Ehinger, M., Goumans, M.-J., Fan, X., Leveen, P., and Karlsson, S. (2003). TGF-{beta} signaling-deficient hematopoietic stem cells have normal self-renewal and regenerative ability in vivo despite increased proliferative capacity in vitro. Blood 102, 3129-3135.

Li, H., Roblin, G., Liu, H., and Heller, S. (2003). From The Cover: Generation of hair cells by stepwise differentiation of embryonic stem cells. PNAS 100, 13495-13500.

Liu, Y., Lyle, S., Yang, Z., and Cotsarelis, G. (2003). Keratin 15 Promoter Targets Putative Epithelial Stem Cells in the Hair Follicle Bulge. J Invest Dermatol 121, 963-968.

Neff, T., Horn, P. A., Peterson, L. J., Thomasson, B. M., Thompson, J., Williams, D. A., Schmidt, M., Georges, G. E., Kalle, C. v., and Kiem, H.-P. (2003). Methylguanine methyltransferase-mediated in vivo selection and chemoprotection of allogeneic stem cells in a large-animal model. J Clin Invest 112, 1581-1588.

Niki, Y., and Mahowald, A. P. (2003). Ovarian cystocytes can repopulate the embryonic germ line and produce functional gametes. PNAS 100, 14042-14045.

Ryu, B. Y., Orwig, K. E., Avarbock, M. R., and Brinster, R. L. (2003). Stem cell and niche development in the postnatal rat testis. Dev Biol 263, 253-263.

Silva, W. A., Jr., Covas, D. T., Panepucci, R. A., Proto-Siqueira, R., Siufi, J. L. C., Zanette, D. L., Santos, A. R. D., and Zago, M. A. (2003). The Profile of Gene Expression of Human Marrow Mesenchymal Stem Cells. Stem Cells 21, 661-669.

Sperger, J. M., Chen, X., Draper, J. S., Antosiewicz, J. E., Chon, C. H., Jones, S. B., Brooks, J. D., Andrews, P. W., Brown, P. O., and Thomson, J. A. (2003). Gene expression patterns in human embryonic stem cells and human pluripotent germ cell tumors. PNAS 100, 13350-13355.

Stopka, T., and Skoultchi, A. I. (2003). The ISWI ATPase Snf2h is required for early mouse development. PNAS 100, 14097-14102.

Taylor, R. W., Barron, M. J., Borthwick, G. M., Gospel, A., Chinnery, P. F., Samuels, D. C., Taylor, G. A., Plusa, S. M., Needham, S. J., Greaves, L. C., et al. (2003). Mitochondrial DNA mutations in human colonic crypt stem cells. J Clin Invest 112, 1351-1360.

Terunuma, A., Jackson, K. L., Kapoor, V., Telford, W. G., and Vogel, J. C. (2003). Side Population Keratinocytes Resembling Bone Marrow Side Population Stem Cells Are Distinct From Label-Retaining Keratinocyte Stem Cells. J Invest Dermatol 121, 1095-1103.

Vitry, S., Bertrand, J. Y., Cumano, A., and Dubois-Dalcq, M. (2003). Primordial Hematopoietic Stem Cells Generate Microglia But Not Myelin-Forming Cells in a Neural Environment. J Neurosci 23, 10724-10731.

Weimann, J. M., Johansson, C. B., Trejo, A., and Blau, H. M. (2003). Stable reprogrammed heterokaryons form spontaneously in Purkinje neurons after bone marrow transplant. Nat Cell Biol 5, 959-966.

Wikramanayake, A. H., Hong, M., Lee, P. N., Pang, K., Byrum, C. A., Bince, J. M., Xu, R., and Martindale, M. Q. (2003). An ancient role for nuclear beta-catenin in the evolution of axial polarity and germ layer segregation. Nature 426, 446-450.

Xu, P., Yoshioka, K., Yoshimura, D., Tominaga, Y., Nishioka, T., Ito, M., and Nakabeppu, Y. (2003a). In Vitro Development of Mouse Embryonic Stem Cells Lacking JNK/Stress-activated Protein Kinase-associated Protein 1 (JSAP1) Scaffold Protein Revealed Its Requirement during Early Embryonic Neurogenesis. J Biol Chem 278, 48422-48433.

Xu, Y., Kimura, K., Matsumoto, N., and Ide, C. (2003b). Isolation of neural stem cells from the forebrain of deceased early postnatal and adult rats with protracted post-mortem intervals. J Neurosci Res 74, 533-540.

Ye, M., Iwasaki, H., Laiosa, C. V., Stadtfeld, M., Xie, H., Heck, S., Clausen, B., Akashi, K., and Graf, T. (2003). Hematopoietic Stem Cells Expressing the Myeloid Lysozyme Gene Retain Long-Term, Multilineage Repopulation Potential. Immunity 19, 689-699.

Zielske, S. P., Reese, J. S., Lingas, K. T., Donze, J. R., and Gerson, S. L. (2003). In vivo selection of MGMT(P140K) lentivirus-transduced human NOD/SCID repopulating cells without pretransplant irradiation conditioning. J Clin Invest 112, 1561-1570.



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October
Updated: March 23, 2004

Aicher, A., Heeschen, C., Mildner-Rihm, C., Urbich, C., Ihling, C., Technau-Ihling, K., Zeiher, A. M., and Dimmeler, S. (2003). Essential role of endothelial nitric oxide synthase for mobilization of stem and progenitor cells. Nat Med 9, 1370 - 1376.

Alvarez-Dolado, M., Pardal, R., Garcia-Verdugo, J. M., Fike, J. R., Lee, H. O., Pfeffer, K., Lois, C., Morrison, S. J., and Alvarez-Buylla, A. (2003). Fusion of bone-marrow-derived cells with Purkinje neurons, cardiomyocytes and hepatocytes. Nature 425, 968-973.

Amsellem, S., Pflumio, F., Bardinet, D., Izac, B., Charneau, P., Romeo, P. H., Dubart-Kupperschmitt, A., and Fichelson, S. (2003). Ex vivo expansion of human hematopoietic stem cells by direct delivery of the HOXB4 homeoprotein. Nat Med 9, 1423-1427.

Bernstein, E., Kim, S. Y., Carmell, M. A., Murchison, E. P., Alcorn, H., Li, M. Z., Mills, A. A., Elledge, S. J., Anderson, K. V., and Hannon, G. J. (2003). Dicer is essential for mouse development. Nat Genet 35, 215-217.

Brazelton, T. R., Nystrom, M., and Blau, H. M. (2003). Significant differences among skeletal muscles in the incorporation of bone marrow-derived cells. Dev Biol 262, 64-74.

Calvi, L. M., Adams, G. B., Weibrecht, K. W., Weber, J. M., Olson, D. P., Knight, M. C., Martin, R. P., Schipani, E., Divieti, P., Bringhurst, F. R., et al. (2003). Osteoblastic cells regulate the haematopoietic stem cell niche. Nature 425, 841-846.

Chen, C. Z., Li, L., Li, M., and Lodish, H. F. (2003). The endoglin(positive) sca-1(positive) rhodamine(low) phenotype defines a near-homogeneous population of long-term repopulating hematopoietic stem cells. Immunity 19, 525-533.

Chen, D., and McKearin, D. (2003). Dpp Signaling Silences bam Transcription Directly to Establish Asymmetric Divisions of Germline Stem Cells. Curr Biol 13, 1786-1791.

Cheung, M., and Briscoe, J. (2003). Neural crest development is regulated by the transcription factor Sox9. Development 130, 5681-5693.

Collombat, P., Mansouri, A., Hecksher-Sorensen, J., Serup, P., Krull, J., Gradwohl, G., and Gruss, P. (2003). Opposing actions of Arx and Pax4 in endocrine pancreas development. Genes Dev 17, 2591-2603.

Evsikov, A. V., and Solter, D. (2003). Comment on " 'Stemness': transcriptional profiling of embryonic and adult stem cells" and "a stem cell molecular signature". Science 302, 393; author reply 393.

Fortunel, N. O., Otu, H. H., Ng, H. H., Chen, J., Mu, X., Chevassut, T., Li, X., Joseph, M., Bailey, C., Hatzfeld, J. A., et al. (2003). Comment on " 'Stemness': transcriptional profiling of embryonic and adult stem cells" and "a stem cell molecular signature". Science 302, 393; author reply 393.

Gabay, L., Lowell, S., Rubin, L. L., and Anderson, D. J. (2003). Deregulation of Dorsoventral Patterning by FGF Confers Trilineage Differentiation Capacity on CNS Stem Cells In Vitro. Neuron 40, 485-499.

Gallardo, T. D., Hammer, R. E., and Garry, D. J. (2003). RNA amplification and transcriptional profiling for analysis of stem cell populations. Genesis 37, 57-63.

Gu, Y., Filippi, M. D., Cancelas, J. A., Siefring, J. E., Williams, E. P., Jasti, A. C., Harris, C. E., Lee, A. W., Prabhakar, R., Atkinson, S. J., et al. (2003). Hematopoietic cell regulation by Rac1 and Rac2 guanosine triphosphatases. Science 302, 445-449.

Haumaitre, C., Reber, M., and Cereghini, S. (2003). Functions of HNF1 Family Members in Differentiation of the Visceral Endoderm Cell Lineage. J Biol Chem 278, 40933-40942.

in 't Anker, P. S., Noort, W. A., Kruisselbrink, A. B., Scherjon, S. A., Beekhuizen, W., Willemze, R., Kanhai, H. H., and Fibbe, W. E. (2003). Nonexpanded primary lung and bone marrow-derived mesenchymal cells promote the engraftment of umbilical cord blood-derived CD34(+) cells in NOD/SCID mice. Exp Hematol 31, 881-889.

Ivanova, N. B., Dimos, J. T., Schaniel, C., Hackney, J. A., Moore, K. A., Ramalho-Santos, M., Yoon, S., Matsuzaki, Y., Mulligan, R. C., Melton, D. A., and Lemischka, I. R. (2003). Response to comments on " 'Stemness': Transcriptional Profiling of Embryonic and Adult Stem Cells" and "A Stem Cell Molecular Signature". Science 302, 393.

Kataoka, K., Medina, R. J., Kageyama, T., Miyazaki, M., Yoshino, T., Makino, T., and Huh, N.-h. (2003). Participation of Adult Mouse Bone Marrow Cells in Reconstitution of Skin. Am J Pathol 163, 1227-1231.

Kaufman, D. S., Lewis, R. L., Hanson, E. T., Auerbach, R., Plendl, J., and Thomson, J. A. (2003). Functional endothelial cells derived from rhesus monkey embryonic stem cells. Blood, 2003-2003-0799.

Krosl, J., Austin, P., Beslu, N., Kroon, E., Humphries, R. K., and Sauvageau, G. (2003). In vitro expansion of hematopoietic stem cells by recombinant TAT-HOXB4 protein. Nat Med 9, 1428 - 1432.

Le Blanc, K., Tammik, C., Rosendahl, K., Zetterberg, E., and Ringden, O. (2003). HLA expression and immunologic propertiesof differentiated and undifferentiated mesenchymal stem cells. Exp Hematol 31, 890-896.

Levenberg, S., Huang, N. F., Lavik, E., Rogers, A. B., Itskovitz-Eldor, J., and Langer, R. (2003). Differentiation of human embryonic stem cells on three-dimensional polymer scaffolds. PNAS 100, 12741-12746.

Levy, Y. S., Merims, D., Panet, H., Barhum, Y., Melamed, E., and Offen, D. (2003). Induction of neuron-specific enolase promoter and neuronal markers in differentiated mouse bone marrow stromal cells. J Mol Neurosci 21, 121-132.

Lieber, J. G., Webb, S., Suratt, B. T., Young, S. K., Johnson, G. L., Keller, G. M., and Worthen, G. S. (2003). The in vitro production and characterization of neutrophils from embryonic stem cells. Blood 103, 852-859.

Luo, Y., Cai, J., Ginis, I., Sun, Y., Lee, S., Yu, S. X., Hoke, A., and Rao, M. (2003). Designing, testing, and validating a focused stem cell microarray for characterization of neural stem cells and progenitor cells. Stem Cells 21, 575-587.

Minguet, S., Cortegano, I., Gonzalo, P., Martinez-Marin, J.-A., Andres, B. d., Salas, C., Melero, D., Gaspar, M.-L., and Marcos, M. A. R. (2003). A population of c-Kitlow(CD45/TER119)- hepatic cell progenitors of 11-day postcoitus mouse embryo liver reconstitutes cell-depleted liver organoids. J Clin Invest 112, 1152-1163.

Modo, M., Cash, D., Mellodew, K., Williams, S. C., Fraser, S. E., Meade, T. J., Price, J., and Hodges, H. (2002). Tracking transplanted stem cell migration using bifunctional, contrast agent-enhanced, magnetic resonance imaging. Neuroimage 17, 803-811.

Mogi, M., Yang, J., Lambert, J.-F., Colvin, G. A., Shiojima, I., Skurk, C., Summer, R., Fine, A., Quesenberry, P. J., and Walsh, K. (2003). Akt Signaling Regulates Side Population Cell Phenotype via Bcrp1 Translocation. J Biol Chem 278, 39068-39075.

Molofsky, A. V., Pardal, R., Iwashita, T., Park, I. K., Clarke, M. F., and Morrison, S. J. (2003). Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation. Nature 425, 962-967.

Murphy, G. J., Gottgens, B., Vegiopoulos, A., Sanchez, M.-J., Leavitt, A. D., Watson, S. P., Green, A. R., and Frampton, J. (2003). Manipulation of Mouse Hematopoietic Progenitors by Specific Retroviral Infection. J Biol Chem 278, 43556-43563.

Nadin, B. M., Goodell, M. A., and Hirschi, K. K. (2003). Phenotype and hematopoietic potential of side population cells throughout embryonic development. Blood 102, 2436-2443.

Parisi, S., D'Andrea, D., Lago, C. T., Adamson, E. D., Persico, M. G., and Minchiotti, G. (2003). Nodal-dependent Cripto signaling promotes cardiomyogenesis and redirects the neural fate of embryonic stem cells. J Cell Biol 163, 303-314.

Peister, A., Mellad, J. A., Larson, B. L., Hall, B. M., Gibson, L. F., and Prockop, D. J. (2003). Adult stem cells from bone marrow (MSCs) isolated from different strains of inbred mice vary in surface epitopes, rates of proliferation, and differentiation potential. Blood, 2003-2009-3070.

Puri, M. C., and Bernstein, A. (2003). Requirement for the TIE family of receptor tyrosine kinases in adult but not fetal hematopoiesis. PNAS 100, 12753-12758.

Tintut, Y., Alfonso, Z., Saini, T., Radcliff, K., Watson, K., Bostrom, K., and Demer, L. L. (2003). Multilineage Potential of Cells From the Artery Wall. Circulation 108, 2505-2510.

Ying, Q.-L., Nichols, J., Chambers, I., and Smith, A. (2003). BMP Induction of Id Proteins Suppresses Differentiation and Sustains Embryonic Stem Cell Self-Renewal in Collaboration with STAT3. Cell 115, 281-292.

Zenzmaier, C., Kollroser, M., Gesslbauer, B., Jandrositz, A., Preisegger, K. H., and Kungl, A. J. (2003). Preliminary 2-D chromatographic investigation of the human stem cell proteome. Biochem Biophys Res Commun 310, 483-490.

Zhang, C. C., and Lodish, H. F. (2003). Insulin-like growth factor 2 expressed in a novel fetal liver cell population is a growth factor for hematopoietic stem cells. Blood, 2003-2008-2955.

Zhang, J., Niu, C., Ye, L., Huang, H., He, X., Tong, W. G., Ross, J., Haug, J., Johnson, T., Feng, J. Q., et al. (2003). Identification of the haematopoietic stem cell niche and control of the niche size. Nature 425, 836-841.



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September 2003
Updated: February 03, 2005

Aubert, J., Stavridis, M. P., Tweedie, S., O'Reilly, M., Vierlinger, K., Li, M., Ghazal, P., Pratt, T., Mason, J. O., Roy, D., and Smith, A. (2003). Screening for mammalian neural genes via fluorescence-activated cell sorter purification of neural precursors from Sox1-gfp knock-in mice . Proc Natl Acad Sci U S A 100 Suppl 1, 11836-11841.

Barberi, T., Klivenyi, P., Calingasan, N. Y., Lee, H., Kawamata, H., Loonam, K., Perrier, A. L., Bruses, J., Rubio, M. E., Topf, N. , et al. (2003). Neural subtype specification of fertilization and nuclear transfer embryonic stem cells and application in parkinsonian mice . Nat Biotechnol 21, 1200 - 1207.

Beltrami, A. P., Barlucchi, L., Torella, D., Baker, M., Limana, F., Chimenti, S., Kasahara, H., Rota, M., Musso, E., Urbanek, K. , et al. (2003). Adult cardiac stem cells are multipotent and support myocardial regeneration . Cell 114, 763-776.

Braun, K. M., Niemann, C., Jensen, U. B., Sundberg, J. P., Silva-Vargas, V., and Watt, F. M. (2003). Manipulation of stem cell proliferation and lineage commitment: visualisation of label-retaining cells in wholemounts of mouse epidermis . Development 130, 5241-5255.

Davidson, A. J., Ernst, P., Wang, Y., Dekens, M. P., Kingsley, P. D., Palis, J., Korsmeyer, S. J., Daley, G. Q., and Zon, L. I. (2003). cdx4 mutants fail to specify blood progenitors and can be rescued by multiple hox genes . Nature 425, 300-306.

Emambokus, N., Vegiopoulos, A., Harman, B., Jenkinson, E., Anderson, G., and Frampton, J. (2003). Progression through key stages of haemopoiesis is dependent on distinct threshold levels of c-Myb . Embo J 22, 4478-4488.

Fehling, H. J., Lacaud, G., Kubo, A., Kennedy, M., Robertson, S., Keller, G., and Kouskoff, V. (2003). Tracking mesoderm induction and its specification to the hemangioblast during embryonic stem cell differentiation . Development 130, 4217-4227.

Ferkowicz, M. J., Starr, M., Xie, X., Li, W., Johnson, S. A., Shelley, W. C., Morrison, P. R., and Yoder, M. C. (2003). CD41 expression defines the onset of primitive and definitive hematopoiesis in the murine embryo . Development 130, 4393-4403.

Jeong, S.-W., Chu, K., Jung, K.-H., Kim, S. U., Kim, M., and Roh, J.-K. (2003). Human Neural Stem Cell Transplantation Promotes Functional Recovery in Rats With Experimental Intracerebral Hemorrhage . Stroke 34, 2258-2263.

Jiang, Y., Henderson, D., Blackstad, M., Chen, A., Miller, R. F., and Verfaillie, C. M. (2003). Neuroectodermal differentiation from mouse multipotent adult progenitor cells . PNAS 100, 11854-11860.

Kaufman, C. K., Zhou, P., Pasolli, H. A., Rendl, M., Bolotin, D., Lim, K.-C., Dai, X., Alegre, M.-L., and Fuchs, E. (2003). GATA-3: an unexpected regulator of cell lineage determination in skin . Genes Dev 17, 2108-2122.

Kokuzawa, J., Yoshimura, S., Kitajima, H., Shinoda, J., Kaku, Y., Iwama, T., Morishita, R., Shimazaki, T., Okano, H., Kunisada, T., and Sakai, N. (2003). Hepatocyte growth factor promotes proliferation and neuronal differentiation of neural stem cells from mouse embryos . Mol Cell Neurosci 24, 190-197.

Kyba, M., Perlingeiro, R. C. R., Hoover, R. R., Lu, C.-W., Pierce, J., and Daley, G. Q. (2003). Enhanced hematopoietic differentiation of embryonic stem cells conditionally expressing Stat5 . PNAS 100, 11904-11910.

Lee, H. S., Crane, G. G., Merok, J. R., Tunstead, J. R., Hatch, N. L., Panchalingam, K., Powers, M. J., Griffith, L. G., and Sherley, J. L. (2003). Clonal expansion of adult rat hepatic stem cell lines by suppression of asymmetric cell kinetics (SACK) . Biotechnol Bioeng 83, 760-771.

Machold, R., Hayashi, S., Rutlin, M., Muzumdar, M. D., Nery, S., Corbin, J. G., Gritli-Linde, A., Dellovade, T., Porter, J. A., Rubin, L. L. , et al. (2003). Sonic hedgehog is required for progenitor cell maintenance in telencephalic stem cell niches . Neuron 39, 937-950.

Mangi, A. A., Noiseux, N., Kong, D., He, H., Rezvani, M., Ingwall, J. S., and Dzau, V. J. (2003). Mesenchymal stem cells modified with Akt prevent remodeling and restore performance of infarcted hearts . Nat Med 9, 1195-1201.

Martin, M. E., Milne, T. A., Bloyer, S., Galoian, K., Shen, W., Gibbs, D., Brock, H. W., Slany, R., and Hess, J. L. (2003). Dimerization of MLL fusion proteins immortalizes hematopoietic cells . Cancer Cell 4, 197-207.

McCroskery, S., Thomas, M., Maxwell, L., Sharma, M., and Kambadur, R. (2003). Myostatin negatively regulates satellite cell activation and self-renewal . J Cell Biol 162, 1135-1147.

McKinney-Freeman, S., Majka, S., Jackson, K., Norwood, K., Hirschi, K., and Goodell, M. (2003). Altered phenotype and reduced function of muscle-derived hematopoietic stem cells. Exp Hematol 31, 806-814.

Mitalipova M, Calhoun J, Shin S, Wininger D, Schulz T, Noggle S, Venable A, Lyons I, Robins A, Stice S (2004). Human embryonic stem cell lines derived from discarded embryos. Stem Cells 21, 521-526.

Nakashima, M., and Reddi, A. H. (2003). The application of bone morphogenetic proteins to dental tissue engineering . Nat Biotechnol 21, 1025-1032.

Pesce, M., Orlandi, A., Iachininoto, M. G., Straino, S., Torella, A. R., Rizzuti, V., Pompilio, G., Bonanno, G., Scambia, G., and Capogrossi, M. C. (2003). Myoendothelial Differentiation of Human Umbilical Cord Blood-Derived Stem Cells in Ischemic Limb Tissues . Circ Res 93, 51e-62.

Reese, J. S., Liu, L., and Gerson, S. L. (2003). Repopulating defect of mismatch repair-deficient hematopoietic stem cells . Blood 102, 1626-1633.

Richards, M., Tan, S., Fong, C.-Y., Biswas, A., Chan, W.-K., and Bongso, A. (2003). Comparative Evaluation of Various Human Feeders for Prolonged Undifferentiated Growth of Human Embryonic Stem Cells . Stem Cells 21, 546-556.

Schneider, T. E., Barland, C., Alex, A. M., Mancianti, M. L., Lu, Y., Cleaver, J. E., Lawrence, H. J., and Ghadially, R. (2003). Measuring stem cell frequency in epidermis: A quantitative in vivo functional assay for long-term repopulating cells . PNAS 100, 11412-11417.

Singh, S. K., Clarke, I. D., Terasaki, M., Bonn, V. E., Hawkins, C., Squire, J., and Dirks, P. B. (2003). Identification of a Cancer Stem Cell in Human Brain Tumors . Cancer Res 63, 5821-5828.

Toyooka, Y., Tsunekawa, N., Akasu, R., and Noce, T. (2003). Embryonic stem cells can form germ cells in vitro . PNAS 100, 11457-11462.

Turnpenny, L., Brickwood, S., Spalluto, C. M., Piper, K., Cameron, I. T., Wilson, D. I., and Hanley, N. A. (2003). Derivation of Human Embryonic Germ Cells: An Alternative Source of Pluripotent Stem Cells . Stem Cells 21, 598-609.

Verstegen, M. M., Wognum, A. W., and Wagemaker, G. (2003). Thrombopoietin is a major limiting factor for selective outgrowth of human umbilical cord blood cells in non-obese diabetic/severe combined immunodeficient recipient mice . Br J Haematol 122, 837-846.

Vrana, K. E., Hipp, J. D., Goss, A. M., McCool, B. A., Riddle, D. R., Walker, S. J., Wettstein, P. J., Studer, L. P., Tabar, V., Cunniff, K. , et al. (2003). Nonhuman primate parthenogenetic stem cells . PNAS 100 Suppl 1, 11911-11916.

Wan, H., Stone, M. G., Simpson, C., Reynolds, L. E., Marshall, J. F., Hart, I. R., Hodivala-Dilke, K. M., and Eady, R. A. J. (2003). Desmosomal proteins, including desmoglein 3, serve as novel negative markers for epidermal stem cell-containing population of keratinocytes . J Cell Sci 116, 4239-4248.

Yamashita, Y. M., Jones, D. L., and Fuller, M. T. (2003). Orientation of Asymmetric Stem Cell Division by the APC Tumor Suppressor and Centrosome . Science 301, 1547-1550.

Youn, Y. H., Feng, J., Tessarollo, L., Ito, K., and Sieber-Blum, M. (2003). Neural crest stem cell and cardiac endothelium defects in the TrkC null mouse . Mol Cell Neurosci 24, 160-170.

August 2003
Updated: April 14, 2004

Ara, T., Tokoyoda, K., Sugiyama, T., Egawa, T., Kawabata, K., and Nagasawa, T. (2003). Long-Term Hematopoietic Stem Cells Require Stromal Cell-Derived Factor-1 for Colonizing Bone Marrow during Ontogeny . Immunity 19, 257-267.

Aravin, A. A., Lagos-Quintana, M., Yalcin, A., Zavolan, M., Marks, D., Snyder, B., Gaasterland, T., Meyer, J., and Tuschl, T. (2003). The small RNA profile during Drosophila melanogaster development . Dev Cell 5, 337-350.

Barbash, I. M., Chouraqui, P., Baron, J., Feinberg, M. S., Etzion, S., Tessone, A., Miller, L., Guetta, E., Zipori, D., Kedes, L. H. , et al. (2003). Systemic delivery of bone marrow-derived mesenchymal stem cells to the infarcted myocardium: feasibility, cell migration, and body distribution . Circulation 108, 863-868.

Bieberich, E., MacKinnon, S., Silva, J., Noggle, S., and Condie, B. G. (2003). Regulation of cell death in mitotic neural progenitor cells by asymmetric distribution of prostate apoptosis response 4 (PAR-4) and simultaneous elevation of endogenous ceramide . J Cell Biol 162, 469-479.

Cairns, L. A., Moroni, E., Levantini, E., Giorgetti, A., Klinger, F. G., Ronzoni, S., Tatangelo, L., Tiveron, C., De Felici, M., Dolci, S. , et al. (2003). Kit regulatory elements required for expression in developing hematopoietic and germ cell lineages . Blood 102, 3954-3962.

Chadwick, K., Wang, L., Li, L., Menendez, P., Murdoch, B., Rouleau, A., and Bhatia, M. (2003). Cytokines and BMP-4 promote hematopoietic differentiation of human embryonic stem cells . Blood 102, 906-915.

D'Amour, K. A., and Gage, F. H. (2003). Genetic and functional differences between multipotent neural and pluripotent embryonic stem cells . Proc Natl Acad Sci U S A 100, 11866-11872.

Galli, C., Lagutina, I., Crotti, G., Colleoni, S., Turini, P., Ponderato, N., Duchi, R., and Lazzari, G. (2003). Pregnancy: a cloned horse born to its dam twin . Nature 424, 635.

Graham, V., Khudyakov, J., Ellis, P., and Pevny, L. (2003). SOX2 Functions to Maintain Neural Progenitor Identity . Neuron 39, 749-765.

Hill, J. M., Dick, A. J., Raman, V. K., Thompson, R. B., Yu, Z. X., Hinds, K. A., Pessanha, B. S., Guttman, M. A., Varney, T. R., Martin, B. J. , et al. (2003). Serial cardiac magnetic resonance imaging of injected mesenchymal stem cells . Circulation 108, 1009-1014.

Hinds, K. A., Hill, J. M., Shapiro, E. M., Laukkanen, M. O., Silva, A. C., Combs, C. A., Varney, T. R., Balaban, R. S., Koretsky, A. P., and Dunbar, C. E. (2003). Highly efficient endosomal labeling of progenitor and stem cells with large magnetic particles allows magnetic resonance imaging of single cells . Blood 102, 867-872.

Houbaviy, H. B., Murray, M. F., and Sharp, P. A. (2003). Embryonic stem cell-specific MicroRNAs . Dev Cell 5, 351-358.

In't Anker, P. S., Noort, W. A., Scherjon, S. A., Kleijburg-Van Der Keur, C., Kruisselbrink, A. B., Van Bezooijen, R. L., Beekhuizen, W., Willemze, R., Kanhai, H. H., and Fibbe, W. E. (2003). Mesenchymal stem cells in human second-trimester bone marrow, liver, lung, and spleen exhibit a similar immunophenotype but a heterogeneous multilineage differentiation potential . Haematologica 88, 845-852.

Iwashita, T., Kruger, G. M., Pardal, R., Kiel, M. J., and Morrison, S. J. (2003). Hirschsprung disease is linked to defects in neural crest stem cell function . Science 301, 972-976.

Kaspar, B. K., Llado, J., Sherkat, N., Rothstein, J. D., and Gage, F. H. (2003). Retrograde viral delivery of IGF-1 prolongs survival in a mouse ALS model . Science 301, 839-842.

Latinkic, B. V., Kotecha, S., and Mohun, T. J. (2003). Induction of cardiomyocytes by GATA4 in Xenopus ectodermal explants . Development 130, 3865-3876.

Li, H., Liu, H., and Heller, S. (2003). Pluripotent stem cells from the adult mouse inner ear . Nat Med 9, 1293 - 1299.

McCauslin, C. S., Wine, J., Cheng, L., Klarmann, K. D., Candotti, F., Clausen, P. A., Spence, S. E., and Keller, J. R. (2003). In vivo retroviral gene transfer by direct intrafemoral injection results in correction of the SCID phenotype in Jak3 knock-out animals . Blood 102, 843-848.

Nemeth, M. J., Curtis, D. J., Kirby, M. R., Garrett-Beal, L. J., Seidel, N. E., Cline, A. P., and Bodine, D. M. (2003). Hmgb3: an HMG-box family member expressed in primitive hematopoietic cells that inhibits myeloid and B-cell differentiation . Blood 102, 1298-1306.

O'Connor-Giles, K. M., and Skeath, J. B. (2003). Numb inhibits membrane localization of Sanpodo, a four-pass transmembrane protein, to promote asymmetric divisions in Drosophila . Dev Cell 5, 231-243.

Oliveira, D. M., and Goodell, M. A. (2003). Transient RNA interference in hematopoietic progenitors with functional consequences . Genesis 36, 203-208.

O'Neill, L. P., Randall, T. E., Lavender, J., Spotswood, H. T., Lee, J. T., and Turner, B. M. (2003). X-linked genes in female embryonic stem cells carry an epigenetic mark prior to the onset of X inactivation . Hum Mol Genet 12, 1783-1790.

Sato, N., Sanjuan, I. M., Heke, M., Uchida, M., Naef, F., and Brivanlou, A. H. (2003). Molecular signature of human embryonic stem cells and its comparison with the mouse . Dev Biol 260, 404-413.

Tsuda, M., Sasaoka, Y., Kiso, M., Abe, K., Haraguchi, S., Kobayashi, S., and Saga, Y. (2003). Conserved role of nanos proteins in germ cell development . Science 301, 1239-1241.

Wislet-Gendebien, S., Leprince, P., Moonen, G., and Rogister, B. (2003). Regulation of neural markers nestin and GFAP expression by cultivated bone marrow stromal cells . J Cell Sci 116, 3295-3302.

Woods, G. L., White, K. L., Vanderwall, D. K., Li, G.-P., Aston, K. I., Bunch, T. D., Meerdo, L. N., and Pate, B. J. (2003). A Mule Cloned from Fetal Cells by Nuclear Transfer . Science 301, 1063.



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July 2003
Updated: February 19, 2004

Allsopp, R. C., Morin, G. B., DePinho, R., Harley, C. B., and Weissman, I. L. (2003). Telomerase is required to slow telomere shortening and extend replicative lifespan of HSCs during serial transplantation. Blood 102, 517-520.

Benveniste, P., Cantin, C., Hyam, D., and Iscove, N. N. (2003). Hematopoietic stem cells engraft in mice with absolute efficiency. Nat Immunol 4, 708-713.

Byrne, J. A., Simonsson, S., Western, P. S., and Gurdon, J. B. (2003). Nuclei of adult mammalian somatic cells are directly reprogrammed to oct-4 stem cell gene expression by amphibian oocytes. Curr Biol 13, 1206-1213.

Cao, B., Zheng, B., Jankowski, R. J., Kimura, S., Ikezawa, M., Deasy, B., Cummins, J., Epperly, M., Qu-Petersen, Z., and Huard, J. (2003). Muscle stem cells differentiate into haematopoietic lineages but retain myogenic potential. Nat Cell Biol 5, 640-646.

Chang, M. Y., Son, H., Lee, Y. S., and Lee, S. H. (2003). Neurons and astrocytes secrete factors that cause stem cells to differentiate into neurons and astrocytes, respectively. Mol Cell Neurosci 23, 414-426.

Cui, Y., Kelleher, E., Straley, E., Fuchs, E., Gorski, K., Levitsky, H., Borrello, I., Civin, C. I., Schoenberger, S. P., Cheng, L., et al. (2003). Immunotherapy of established tumors using bone marrow transplantation with antigen gene--modified hematopoietic stem cells. Nat Med 9, 952-958.

Danet, G. H., Pan, Y., Luongo, J. L., Bonnet, D. A., and Simon, M. C. (2003). Expansion of human SCID-repopulating cells under hypoxic conditions. J Clin Invest 112, 126-135.

Emambokus, N. R., and Frampton, J. (2003). The glycoprotein IIb molecule is expressed on early murine hematopoietic progenitors and regulates their numbers in sites of hematopoiesis. Immunity 19, 33-45.

Gilchrist, D. S., Ure, J., Hook, L., and Medvinsky, A. (2003). Labeling of hematopoietic stem and progenitor cells in novel activatable EGFP reporter mice. Genesis 36, 168-176.

Hess, D., Li, L., Martin, M., Sakano, S., Hill, D., Strutt, B., Thyssen, S., Gray, D. A., and Bhatia, M. (2003). Bone marrow-derived stem cells initiate pancreatic regeneration. Nat Biotechnol 21, 763-770.

Kale, S., Karihaloo, A., Clark, P. R., Kashgarian, M., Krause, D. S., and Cantley, L. G. (2003). Bone marrow stem cells contribute to repair of the ischemically injured renal tubule. J Clin Invest 112, 42-49.

Kollet, O., Shivtiel, S., Chen, Y. Q., Suriawinata, J., Thung, S. N., Dabeva, M. D., Kahn, J., Spiegel, A., Dar, A., Samira, S., et al. (2003). HGF, SDF-1, and MMP-9 are involved in stress-induced human CD34+ stem cell recruitment to the liver. J Clin Invest 112, 160-169.

Lee, B. C., Cheng, T., Adams, G. B., Attar, E. C., Miura, N., Lee, S. B., Saito, Y., Olszak, I., Dombkowski, D., Olson, D. P., et al. (2003). P2Y-like receptor, GPR105 (P2Y14), identifies and mediates chemotaxis of bone-marrow hematopoietic stem cells. Genes Dev 17, 1592-1604.

Persons, D. A., Allay, E. R., Sawai, N., Hargrove, P. W., Brent, T. P., Hanawa, H., Nienhuis, A. W., and Sorrentino, B. P. (2003). Successful treatment of murine beta-thalassemia using in vivo selection of genetically modified, drug-resistant hematopoietic stem cells. Blood 102, 506-513.

Sampaolesi, M., Torrente, Y., Innocenzi, A., Tonlorenzi, R., D'Antona, G., Pellegrino, M.A., Barresi, R., Bresolin, N., De Angelis, M. G., Campbell, K. P., et al. (2003). Cell therapy of alpha-sarcoglycan null dystrophic mice through intra-arterial delivery of mesoangioblasts. Science 301, 487-492.

Song, X., and Xie, T. (2003). Wingless signaling regulates the maintenance of ovarian somatic stem cells in Drosophila. Development 130, 3259-3268.

Stolt, C. C., Lommes, P., Sock, E., Chaboissier, M. C., Schedl, A., and Wegner, M. (2003). The Sox9 transcription factor determines glial fate choice in the developing spinal cord. Genes Dev 17, 1677-1689.

Terskikh, A. V., Miyamoto, T., Chang, C., Diatchenko, L., and Weissman, I. L. (2003). Gene expression analysis of purified hematopoietic stem cells and committed progenitors. Blood 102, 94-101.

Wright, L. S., Li, J., Caldwell, M. A., Wallace, K., Johnson, J. A., and Svendsen, C. N. (2003). Gene expression in human neural stem cells: effects of leukemia inhibitory factor. J Neurochem 86, 179-195.



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June 2003
Updated: March 23, 2004

Bjornsson, J. M., Larsson, N., Brun, A. C., Magnusson, M., Andersson, E., Lundstrom, P., Larsson, J., Repetowska, E., Ehinger, M., Humphries, R. K., and Karlsson, S. (2003). Reduced proliferative capacity of hematopoietic stem cells deficient in Hoxb3 and Hoxb4. Mol Cell Biol 23, 3872-3883.

Coppo, P., Dusanter-Fourt, I., Millot, G., Nogueira, M. M., Dugray, A., Bonnet, M. L., Mitjavila-Garcia, M. T., Le Pesteur, D., Guilhot, F., Vainchenker, W., et al. (2003). Constitutive and specific activation of STAT3 by BCR-ABL in embryonic stem cells. Oncogene 22, 4102-4110.

De Palma, M., Venneri, M. A., Roca, C., and Naldini, L. (2003). Targeting exogenous genes to tumor angiogenesis by transplantation of genetically modified hematopoietic stem cells. Nat Med 9, 789-795.

Kerr, D. A., Llado, J., Shamblott, M. J., Maragakis, N. J., Irani, D. N., Crawford, T. O., Krishnan, C., Dike, S., Gearhart, J. D., and Rothstein, J. D. (2003). Human embryonic germ cell derivatives facilitate motor recovery of rats with diffuse motor neuron injury. J Neurosci 23, 5131-5140.

Lambert, J. F., Liu, M., Colvin, G. A., Dooner, M., McAuliffe, C. I., Becker, P. S., Forget, B. G., Weissman, S. M., and Quesenberry, P. J. (2003). Marrow stem cells shift gene expression and engraftment phenotype with cell cycle transit. J Exp Med 197, 1563-1572.

Lin, J. C., and Rosenthal, A. (2003). Molecular mechanisms controlling the development of dopaminergic neurons. Semin Cell Dev Biol 14, 175-180.

Migishima, F., Oikawa, A., Kondo, S., Ema, H., Morita, Y., Nakauchi, H., Yokoyama, M., Song, S. Y., Nishijima, M., Okabe, M., and Shinohara, N. (2003). Full reconstitution of hematopoietic system by murine umbilical cord blood. Transplantation 75, 1820-1826.

Newsome, P. N., Johannessen, I., Boyle, S., Dalakas, E., McAulay, K. A., Samuel, K., Rae, F., Forrester, L., Turner, M. L., Hayes, P. C., et al. (2003). Human cord blood-derived cells can differentiate into hepatocytes in the mouse liver with no evidence of cellular fusion. Gastroenterology 124, 1891-1900.

Polesskaya, A., Seale, P., and Rudnicki, M. A. (2003). Wnt signaling induces the myogenic specification of resident CD45+ adult stem cells during muscle regeneration. Cell 113, 841-852.

Schwenk, F., Zevnik, B., Bruning, J., Rohl, M., Willuweit, A., Rode, A., Hennek, T., Kauselmann, G., Jaenisch, R., and Kuhn, R. (2003). Hybrid embryonic stem cell-derived tetraploid mice show apparently normal morphological, physiological, and neurological characteristics. Mol Cell Biol 23, 3982-3989.

Stepanovic, V., Awad, O., Jiao, C., Dunnwald, M., and Schatteman, G. C. (2003). Leprdb diabetic mouse bone marrow cells inhibit skin wound vascularization but promote wound healing. Circ Res 92, 1247-1253.

Sun, Y. E., Martinowich, K., and Ge, W. (2003). Making and repairing the mammalian brain--signaling toward neurogenesis and gliogenesis. Semin Cell Dev Biol 14, 161-168.

Suzuki, A., Iwama, A., Miyashita, H., Nakauchi, H., and Taniguchi, H. (2003). Role for growth factors and extracellular matrix in controlling differentiation of prospectively isolated hepatic stem cells. Development 130, 2513-2524.

Zhu, C. H., and Xie, T. (2003). Clonal expansion of ovarian germline stem cells during niche formation in Drosophila. Development 130, 2579-2588.



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May 2003
Updated: April 14, 2004

Bonyadi, M., Waldman, S. D., Liu, D., Aubin, J. E., Grynpas, M. D., and Stanford, W. L. (2003). Mesenchymal progenitor self-renewal deficiency leads to age-dependent osteoporosis in Sca-1/Ly-6A null mice . Proc Natl Acad Sci U S A 100, 5840-5845.

Brivanlou, A. H., Gage, F. H., Jaenisch, R., Jessell, T., Melton, D., and Rossant, J. (2003). STEM CELLS: Enhanced: Setting Standards for Human Embryonic Stem Cells. Science 300, 913-916.

Chambers, I., Colby, D., Robertson, M., Nichols, J., Lee, S., Tweedie, S., and Smith, A. (2003). Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells . Cell 113, 643-655.

Coraux, C., Hilmi, C., Rouleau, M., Spadafora, A., Hinnrasky, J., Ortonne, J. P., Dani, C., and Aberdam, D. (2003). Reconstituted skin from murine embryonic stem cells . Curr Biol 13, 849-853.

Dontu, G., Abdallah, W. M., Foley, J. M., Jackson, K. W., Clarke, M. F., Kawamura, M. J., and Wicha, M. S. (2003). In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells . Genes Dev 17, 1253-1270.

Gronthos, S., Zannettino, A. C., Hay, S. J., Shi, S., Graves, S. E., Kortesidis, A., and Simmons, P. J. (2003). Molecular and cellular characterisation of highly purified stromal stem cells derived from human bone marrow . J Cell Sci 116, 1827-1835.

Hubner, K., Fuhrmann, G., Christenson, L. K., Kehler, J., Reinbold, R., De La Fuente, R., Wood, J., Strauss, J. F., 3rd, Boiani, M., and Scholer, H. R. (2003). Derivation of oocytes from mouse embryonic stem cells . Science 300, 1251-1256.

Katayama, Y., Hidalgo, A., Furie, B. C., Vestweber, D., Furie, B., and Frenette, P. S. (2003). PSGL-1 participates in E-selectin-mediated progenitor homing to bone marrow: evidence for cooperation between E-selectin ligands and {alpha}4 integrin. Blood 102, 2060-2067.

Kraitchman, D. L., Heldman, A. W., Atalar, E., Amado, L. C., Martin, B. J., Pittenger, M. F., Hare, J. M., and Bulte, J. W. (2003). In vivo magnetic resonance imaging of mesenchymal stem cells in myocardial infarction . Circulation 107, 2290-2293.

Kumano, K., Chiba, S., Kunisato, A., Sata, M., Saito, T., Nakagami-Yamaguchi, E., Yamaguchi, T., Masuda, S., Shimizu, K., Takahashi, T. , et al. (2003). Notch1 but not Notch2 is essential for generating hematopoietic stem cells from endothelial cells . Immunity 18, 699-711.

Lessard, J., and Sauvageau, G. (2003). Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells . Nature 423, 255-260.

Mitsui, K., Tokuzawa, Y., Itoh, H., Segawa, K., Murakami, M., Takahashi, K., Maruyama, M., Maeda, M., and Yamanaka, S. (2003). The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells . Cell 113, 631-642.

Park, I. K., Qian, D., Kiel, M., Becker, M. W., Pihalja, M., Weissman, I. L., Morrison, S. J., and Clarke, M. F. (2003). Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells . Nature 423, 302-305.

Reya, T., Duncan, A. W., Ailles, L., Domen, J., Scherer, D. C., Willert, K., Hintz, L., Nusse, R., and Weissman, I. L. (2003). A role for Wnt signalling in self-renewal of haematopoietic stem cells . Nature 423, 409-414.

Takahashi, K., Mitsui, K., and Yamanaka, S. (2003). Role of ERas in promoting tumour-like properties in mouse embryonic stem cells . Nature 423, 541-545.

Ueno, H., Sakita-Ishikawa, M., Morikawa, Y., Nakano, T., Kitamura, T., and Saito, M. (2003). A stromal cell-derived membrane protein that supports hematopoietic stem cells . Nat Immunol 4, 457-463.

Wang, X., Ge, S., McNamara, G., Hao, Q. L., Crooks, G. M., and Nolta, J. A. (2003). Albumin-expressing hepatocyte-like cells develop in the livers of immune-deficient mice that received transplants of highly purified human hematopoietic stem cells . Blood 101, 4201-4208.

April 2003
Updated: February 19, 2004

Alberta, J. A., Springett, G. M., Rayburn, H., Natoli, T. A., Loring, J., Kreidberg, J. A., and Housman, D. (2003). Role of the WT1 tumor suppressor in murine hematopoiesis. Blood 101, 2570-2574.

Allsopp, R. C., Morin, G. B., Horner, J. W., DePinho, R., Harley, C. B., and Weissman, I. L. (2003). Effect of TERT over-expression on the long-term transplantation capacity of hematopoietic stem cells. Nat Med 9, 369-371.

Bortvin, A., Eggan, K., Skaletsky, H., Akutsu, H., Berry, D. L., Yanagimachi, R., Page, D. C., and Jaenisch, R. (2003). Incomplete reactivation of Oct4-related genes in mouse embryos cloned from somatic nuclei. Development 130, 1673-1680.

Grandbarbe, L., Bouissac, J., Rand, M., Hrabe de Angelis, M., Artavanis-Tsakonas, S., and Mohier, E. (2003). Delta-Notch signaling controls the generation of neurons/glia from neural stem cells in a stepwise process. Development 130, 1391-1402.

Kai, T., and Spradling, A. (2003). An empty Drosophila stem cell niche reactivates the proliferation of ectopic cells. Proc Natl Acad Sci U S A 100, 4633-4638.

Kim, J., Lo, L., Dormand, E., and Anderson, D. J. (2003). SOX10 maintains multipotency and inhibits neuronal differentiation of neural crest stem cells. Neuron 38, 17-31.

Krosl, J., Beslu, N., Mayotte, N., Humphries, R. K., and Sauvageau, G. (2003). The competitive nature of HOXB4-transduced HSC is limited by PBX1: the generation of ultra-competitive stem cells retaining full differentiation potential. Immunity 18, 561-571.

Simerly, C., Dominko, T., Navara, C., Payne, C., Capuano, S., Gosman, G., Chong, K. Y., Takahashi, D., Chace, C., Compton, D., et al. (2003). Molecular correlates of primate nuclear transfer failures. Science 300, 297.

Sordella, R., Jiang, W., Chen, G. C., Curto, M., and Settleman, J. (2003). Modulation of Rho GTPase signaling regulates a switch between adipogenesis and myogenesis. Cell 113, 147-158.

Vassilopoulos, G., Wang, P. R., and Russell, D. W. (2003). Transplanted bone marrow regenerates liver by cell fusion. Nature 422, 901-904.

Wang, J., Kimura, T., Asada, R., Harada, S., Yokota, S., Kawamoto, Y., Fujimura, Y., Tsuji, T., Ikehara, S., and Sonoda, Y. (2003a). SCID-repopulating cell activity of human cord blood-derived CD34- cells assured by intra-bone marrow injection. Blood 101, 2924-2931.

Wang, X., Willenbring, H., Akkari, Y., Torimaru, Y., Foster, M., Al-Dhalimy, M., Lagasse, E., Finegold, M., Olson, S., and Grompe, M. (2003b). Cell fusion is the principal source of bone-marrow-derived hepatocytes. Nature 422, 897-901.

Yahata, T., Ando, K., Sato, T., Miyatake, H., Nakamura, Y., Muguruma, Y., Kato, S., and Hotta, T. (2003). A highly sensitive strategy for SCID-repopulating cell assay by direct injection of primitive human hematopoietic cells into NOD/SCID mice bone marrow. Blood 101, 2905-2913.

Yang, Y., and Seed, B. (2003). Site-specific gene targeting in mouse embryonic stem cells with intact bacterial artificial chromosomes. Nat Biotechnol 21, 447-451.



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March 2003
Updated: February 19, 2004

Chen, D., and McKearin, D. M. (2003). A discrete transcriptional silencer in the bam gene determines asymmetric division of the Drosophila germline stem cell. Development 130, 1159-1170.

Chojnacki, A., Shimazaki, T., Gregg, C., Weinmaster, G., and Weiss, S. (2003). Glycoprotein 130 signaling regulates Notch1 expression and activation in the self-renewal of mammalian forebrain neural stem cells. J Neurosci 23, 1730-1741.

De Bari, C., Dell'Accio, F., Vandenabeele, F., Vermeesch, J. R., Raymackers, J. M., and Luyten, F. P. (2003). Skeletal muscle repair by adult human mesenchymal stem cells from synovial membrane. J Cell Biol 160, 909-918.

Jamora, C., DasGupta, R., Kocieniewski, P., and Fuchs, E. (2003). Links between signal transduction, transcription and adhesion in epithelial bud development. Nature 422, 317-322.

Klein, C., Nguyen, D., Liu, C. H., Mizoguchi, A., Bhan, A. K., Miki, H., Takenawa, T., Rosen, F. S., Alt, F. W., Mulligan, R. C., and Snapper, S. B. (2003). Gene therapy for Wiskott-Aldrich syndrome: rescue of T-cell signaling and amelioration of colitis upon transplantation of retrovirally transduced hematopoietic stem cells in mice. Blood 101, 2159-2166.

Kunisato, A., Chiba, S., Nakagami-Yamaguchi, E., Kumano, K., Saito, T., Masuda, S., Yamaguchi, T., Osawa, M., Kageyama, R., Nakauchi, H., et al. (2003). HES-1 preserves purified hematopoietic stem cells ex vivo and accumulates side population cells in vivo. Blood 101, 1777-1783.

Laufs, S., Gentner, B., Nagy, K. Z., Jauch, A., Benner, A., Naundorf, S., Kuehlcke, K., Schiedlmeier, B., Ho, A. D., Zeller, W. J., and Fruehauf, S. (2003). Retroviral vector integration occurs in preferred genomic targets of human bone marrow-repopulating cells. Blood 101, 2191-2198.

Masuya, M., Drake, C. J., Fleming, P. A., Reilly, C. M., Zeng, H., Hill, W. D., Martin-Studdard, A., Hess, D. C., and Ogawa, M. (2003). Hematopoietic origin of glomerular mesangial cells. Blood 101, 2215-2218.

Mathe, E., Inoue, Y. H., Palframan, W., Brown, G., and Glover, D. M. (2003). Orbit/Mast, the CLASP orthologue of Drosophila, is required for asymmetric stem cell and cystocyte divisions and development of the polarised microtubule network that interconnects oocyte and nurse cells during oogenesis. Development 130, 901-915.

Murdoch, B., Chadwick, K., Martin, M., Shojaei, F., Shah, K. V., Gallacher, L., Moon, R. T., and Bhatia, M. (2003). Wnt-5A augments repopulating capacity and primitive hematopoietic development of human blood stem cells in vivo. Proc Natl Acad Sci U S A 100, 3422-3427.

Nakamura, T., Shiojima, S., Hirai, Y., Iwama, T., Tsuruzoe, N., Hirasawa, A., Katsuma, S., and Tsujimoto, G. (2003). Temporal gene expression changes during adipogenesis in human mesenchymal stem cells. Biochem Biophys Res Commun 303, 306-312.

Orelio, C., and Dzierzak, E. (2003). Identification of 2 novel genes developmentally regulated in the mouse aorta-gonad-mesonephros region. Blood 101, 2246-2249.

Petersen, B. E., Grossbard, B., Hatch, H., Pi, L., Deng, J., and Scott, E. W. (2003). Mouse A6-positive hepatic oval cells also express several hematopoietic stem cell markers. Hepatology 37, 632-640.

Rubinson, D. A., Dillon, C. P., Kwiatkowski, A. V., Sievers, C., Yang, L., Kopinja, J., Rooney, D. L., Ihrig, M. M., McManus, M. T., Gertler, F. B., et al. (2003). A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference. Nat Genet 33, 401-406.

Schiedlmeier, B., Klump, H., Will, E., Arman-Kalcek, G., Li, Z., Wang, Z., Rimek, A., Friel, J., Baum, C., and Ostertag, W. (2003). High-level ectopic HOXB4 expression confers a profound in vivo competitive growth advantage on human cord blood CD34+ cells, but impairs lymphomyeloid differentiation. Blood 101, 1759-1768.

Spees, J. L., Olson, S. D., Ylostalo, J., Lynch, P. J., Smith, J., Perry, A., Peister, A., Wang, M. Y., and Prockop, D. J. (2003). Differentiation, cell fusion, and nuclear fusion during ex vivo repair of epithelium by human adult stem cells from bone marrow stroma. Proc Natl Acad Sci U S A 100, 2397-2402.

Steidl, U., Kronenwett, R., Rohr, U. P., Fenk, R., Kliszewski, S., Maercker, C., Neubert, P., Aivado, M., Koch, J., Modlich, O., et al. (2002). Gene expression profiling identifies significant differences between the molecular phenotypes of bone marrow-derived and circulating human CD34+ hematopoietic stem cells. Blood 99, 2037-2044.

Suzawa, M., Takada, I., Yanagisawa, J., Ohtake, F., Ogawa, S., Yamauchi, T., Kadowaki, T., Takeuchi, Y., Shibuya, H., Gotoh, Y., et al. (2003). Cytokines suppress adipogenesis and PPAR-gamma function through the TAK1/TAB1/NIK cascade. Nat Cell Biol 5, 224-230.

Zwaka, T. P., and Thomson, J. A. (2003). Homologous recombination in human embryonic stem cells. Nat Biotechnol 21, 319-321.



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February 2003
Updated: June 23, 2004

Blyszczuk, P., Czyz, J., Kania, G., Wagner, M., Roll, U., St-Onge, L., and Wobus, A. M. (2003). Expression of Pax4 in embryonic stem cells promotes differentiation of nestin-positive progenitor and insulin-producing cells. Proc Natl Acad Sci U S A 100, 998-1003.

de Haan, G., Weersing, E., Dontje, B., van Os, R., Bystrykh, L. V., Vellenga, E., and Miller, G. (2003). In vitro generation of long-term repopulating hematopoietic stem cells by fibroblast growth factor-1. Dev Cell 4, 241-251.

Gropp, M., Itsykson, P., Singer, O., Ben-Hur, T., Reinhartz, E., Galun, E., and Reubinoff, B. E. (2003). Stable genetic modification of human embryonic stem cells by lentiviral vectors. Mol Ther 7 , 281-287.

Kuci, S., Wessels, J. T., Buhring, H. J., Schilbach, K., Schumm, M., Seitz, G., Loffler, J., Bader, P., Schlegel, P. G., Niethammer, D., and Handgretinger, R. (2003). Identification of a novel class of human adherent CD34- stem cells that give rise to SCID-repopulating cells. Blood 101, 869-876.

Magrassi, L., Castello, S., Ciardelli, L., Podesta, M., Gasparoni, A., Conti, L., Pezzotta, S., Frassoni, F., and Cattaneo, E. (2003). Freshly dissociated fetal neural stem/progenitor cells do not turn into blood. Mol Cell Neurosci 22, 179-187.

Mezey, E., Key, S., Vogelsang, G., Szalayova, I., Lange, G. D., and Crain, B. (2003). Transplanted bone marrow generates new neurons in human brains. Proc Natl Acad Sci U S A 100, 1364-1369.

Nilsson, S. K., Haylock, D. N., Johnston, H. M., Occhiodoro, T., Brown, T. J., and Simmons, P. J. (2003). Hyaluronan is synthesized by primitive hemopoietic cells, participates in their lodgment at the endosteum following transplantation, and is involved in the regulation of their proliferation and differentiation in vitro. Blood 101, 856-862.

Takeuchi, A., Mishina, Y., Miyaishi, O., Kojima, E., Hasegawa, T., and Isobe, K. (2003). Heterozygosity with respect to Zfp148 causes complete loss of fetal germ cells during mouse embryogenesis. Nat Genet 33, 172-176.

Woods, N. B., Muessig, A., Schmidt, M., Flygare, J., Olsson, K., Salmon, P., Trono, D., von Kalle, C., and Karlsson, S. (2003). Lentiviral vector transduction of NOD/SCID repopulating cells results in multiple vector integrations per transduced cell: risk of insertional mutagenesis. Blood 101, 1284-1289.

Yamamoto, N., Tanigaki, K., Han, H., Hiai, H., and Honjo, T. (2003). Notch/RBP-J Signaling Regulates Epidermis/Hair Fate Determination of Hair Follicular Stem Cells. Curr Biol 13, 333-338.

Ying, Q. L., Stavridis, M., Griffiths, D., Li, M., and Smith, A. (2003). Conversion of embryonic stem cells into neuroectodermal precursors in adherent monoculture. Nat Biotechnol 21, 183-186.



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January 2003
Updated: February 19, 2004

Akashi, K., He, X., Chen, J., Iwasaki, H., Niu, C., Steenhard, B., Zhang, J., Haug, J., and Li, L. (2003). Transcriptional accessibility for genes of multiple tissues and hematopoietic lineages is hierarchically controlled during early hematopoiesis. Blood 101, 383-389.

Beilhack, G. F., Scheffold, Y. C., Weissman, I. L., Taylor, C., Jerabek, L., Burge, M. J., Masek, M. A., and Shizuru, J. A. (2003). Purified allogeneic hematopoietic stem cell transplantation blocks diabetes pathogenesis in NOD mice. Diabetes 52, 59-68.

Bello, B. C., Hirth, F., and Gould, A. P. (2003). A pulse of the Drosophila Hox protein Abdominal-A schedules the end of neural proliferation via neuroblast apoptosis. Neuron 37, 209-219.

Cai, Y., Yu, F., Lin, S., Chia, W., and Yang, X. (2003). Apical complex genes control mitotic spindle geometry and relative size of daughter cells in Drosophila neuroblast and pI asymmetric divisions. Cell 112, 51-62.

Gough, P. J., and Raines, E. W. (2003). Gene therapy of apolipoprotein E-deficient mice using a novel macrophage-specific retroviral vector. Blood 101, 485-491.

Ito, C. Y., Li, C. Y., Bernstein, A., Dick, J. E., and Stanford, W. L. (2003). Hematopoietic stem cell and progenitor defects in Sca-1/Ly-6A-null mice. Blood 101, 517-523.

Lai, K., Kaspar, B. K., Gage, F. H., and Schaffer, D. V. (2003). Sonic hedgehog regulates adult neural progenitor proliferation in vitro and in vivo. Nat Neurosci 6, 21-27.

Mikkola, H. K., Fujiwara, Y., Schlaeger, T. M., Traver, D., and Orkin, S. H. (2003a). Expression of CD41 marks the initiation of definitive hematopoiesis in the mouse embryo. Blood 101, 508-516.

Mikkola, H. K., Klintman, J., Yang, H., Hock, H., Schlaeger, T. M., Fujiwara, Y., and Orkin, S. H. (2003b). Haematopoietic stem cells retain long-term repopulating activity and multipotency in the absence of stem-cell leukaemia SCL/tal-1 gene. Nature 421, 547-551.

Pierce, E. A., Liu, Q., Igoucheva, O., Omarrudin, R., Ma, H., Diamond, S. L., and Yoon, K. (2003). Oligonucleotide-directed single-base DNA alterations in mouse embryonic stem cells. Gene Ther 10, 24-33.

Rabinovsky, E. D., Gelir, E., Gelir, S., Lui, H., Kattash, M., DeMayo, F. J., Shenaq, S. M., and Schwartz, R. J. (2003). Targeted expression of IGF-1 transgene to skeletal muscle accelerates muscle and motor neuron regeneration. Faseb J 17, 53-55.

Rajagopal, J., Anderson, W. J., Kume, S., Martinez, O. I., and Melton, D. A. (2003). Insulin staining of ES cell progeny from insulin uptake. Science 299, 363.

Roelofs, H., de Pauw, E. S., Zwinderman, A. H., Opdam, S. M., Willemze, R., Tanke, H. J., and Fibbe, W. E. (2003). Homeostasis of telomere length rather than telomere shortening after allogeneic peripheral blood stem cell transplantation. Blood 101, 358-362.

Stamm, C., Westphal, B., Kleine, H. D., Petzsch, M., Kittner, C., Klinge, H., Schumichen, C., Nienaber, C. A., Freund, M., and Steinhoff, G. (2003). Autologous bone-marrow stem-cell transplantation for myocardial regeneration. Lancet 361, 45-46.

Tateishi, S., Niwa, H., Miyazaki, J., Fujimoto, S., Inoue, H., and Yamaizumi, M. (2003). Enhanced genomic instability and defective postreplication repair in RAD18 knockout mouse embryonic stem cells. Mol Cell Biol 23, 474-481.

Vacek, M. M., Ma, H., Gemignani, F., Lacerra, G., Kafri, T., and Kole, R. (2003). High-level expression of hemoglobin A in human thalassemic erythroid progenitor cells following lentiviral vector delivery of an antisense snRNA. Blood 101, 104-111.

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