ISSCR :: Stem Cell Science Literature

Stem Cell Science Literature

Literature Highlights

2006 Literature
Click on the month to see the literature highlights from that month or scroll through the list.

January February March

April May June

July August September

October November December

EndNote files

December 12, 2006

On preventing fraud

Kennedy, D. (2006). Responding to fraud. Science 314, 1353.

Review

Seydoux, G., and Braun, R. E. (2006). Pathway to totipotency: lessons from germ cells. Cell 127, 891-904.

Reviews of recent literature

Chamberlain, J. S. (2006). Stem-cell biology: a move in the right direction. Nature 444, 552-553.
On the findings of Sampaolesi et al., 2006 (see below)

Dirks, P. B. (2006). Cancer: Stem cells and brain tumours. Nature 444, 687-688.
On the findings of Bao et al., 2006 and Piccirillo et al., 2006 (see below)

Simpson, J. L. (2006). Medicine: blastomeres and stem cells. Nature 444, 432-435.
On the findings of Klimanskaya et al., 2006 (see below)

Technology

Strauss, E. (2006). Arrays of hope. Cell 127, 657-659.
Discusses papers in the September 2006 issue of Nature Biotechnology that present the first formal results of the MicroArray Quality Control (MAQC) project

Shianna, K. V., and Willard, H. F. (2006). Human genomics: in search of normality. Nature 444, 428-429.
Discusses the generation of the first map of copy-number variation in the human genome, another resource for studies of genome structure and human disease

Articles

Bao, S., Wu, Q., McLendon, R. E., Hao, Y., Shi, Q., Hjelmeland, A. B., Dewhirst, M. W., Bigner, D. D., and Rich, J. N. (2006). Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature 444, 756-760.

Gouon-Evans, V., Boussemart, L., Gadue, P., Nierhoff, D., Koehler, C. I., Kubo, A., Shafritz, D. A., and Keller, G. (2006). BMP-4 is required for hepatic specification of mouse embryonic stem cell-derived definitive endoderm. Nat Biotechnol 24, 1402-1411.

Klimanskaya, I., Chung, Y., Becker, S., Lu, S. J., and Lanza, R. (2006). Human embryonic stem cell lines derived from single blastomeres. Nature 444, 481-485.
See also addendum: Nature 444, 512

Moretti, A., Caron, L., Nakano, A., Lam, J. T., Bernshausen, A., Chen, Y., Qyang, Y., Bu, L., Sasaki, M., Martin-Puig, S., et al. (2006). Multipotent Embryonic Isl1(+) Progenitor Cells Lead to Cardiac, Smooth Muscle, and Endothelial Cell Diversification. Cell. doi:10.1016/j.cell.2006.10.029
See also Wu et al., 2006 (below) and Kattman et al., 2006 Dev Cell 11, 723-732 (November Pulse)

Piccirillo, S. G., Reynolds, B. A., Zanetti, N., Lamorte, G., Binda, E., Broggi, G., Brem, H., Olivi, A., Dimeco, F., and Vescovi, A. L. (2006). Bone morphogenetic proteins inhibit the tumorigenic potential of human brain tumour-initiating cells. Nature 444, 761-765.

Sampaolesi, M., Blot, S., D'Antona, G., Granger, N., Tonlorenzi, R., Innocenzi, A., Mognol, P., Thibaud, J. L., Galvez, B. G., Barthelemy, I., et al. (2006). Mesoangioblast stem cells ameliorate muscle function in dystrophic dogs. Nature 444, 574-579.

Wang, J., Rao, S., Chu, J., Shen, X., Levasseur, D. N., Theunissen, T. W., and Orkin, S. H. (2006). A protein interaction network for pluripotency of embryonic stem cells. Nature 444, 364-368.

Wu, S. M., Fujiwara, Y., Cibulsky, S. M., Clapham, D. E., Lien, C. L., Schultheiss, T. M., and Orkin, S. H. (2006). Developmental Origin of a Bipotential Myocardial and Smooth Muscle Cell Precursor in the Mammalian Heart. Cell. doi:10.1016/j.cell.2006.10.028
See also Moretti et al., 2006 (above) and Kattman et al., 2006 Dev Cell 11, 723-732 (November Pulse)

November 14, 2006

Health Policy:

Halme, D. G., and Kessler, D. A. (2006). FDA regulation of stem-cell-based therapies. N Engl J Med 355, 1730-1735.

Schwartz, R. S. (2006). The politics and promise of stem-cell research. N Engl J Med 355, 1189-1191.
Summarizes the findings of three recent NEJM papers that report on clinical trials of adult hematopoietic stem cells as a treatment for cardiovascular disease.

Reviews of recent literature:

Beausejour, C. M., and Campisi, J. (2006). Ageing: balancing regeneration and cancer. Nature 443, 404-405.
Outlines three recent Nature papers that describe a role for p16 INK4a in cellular senescence in stem/progenitor cells illustrating the delicate balance of regeneration against the risks of hyper-proliferative diseases.

Kim, W. Y., and Sharpless, N. E. (2006). The regulation of INK4/ARF in cancer and aging. Cell 127, 265-275.
A more in-depth review on p16 INK4a

Carson, C. T., Aigner, S., and Gage, F. H. (2006). Stem cells: the good, bad and barely in control. Nat Med 12, 1237-1238.
Commentary on the findings of Roy et al., 2006 (see below)

Curado, S., and Stainier, D. Y. (2006). The HeArt of Regeneration. Cell 127, 462-464.
Commentary on the findings of Lepilina et al., 2006 (see below)

Holden, C. (2006). Stem cells. Scientists create human stem cell line from “dead” embryos. Science 313, 1869.
Commentary on the findings of Zhang et al., 2006 (see below)

Reh, T. A. (2006) Neurobiology: Right timing for retina repair. Nature. doi:10.1038/444156a
Commentary on the findings of MacLaren et al., 2006 (see below)

Papers:

Chen, S., Do, J. T., Zhang, Q., Yao, S., Yan, F., Peters, E. C., Scholer, H. R., Schultz, P. G., and Ding, S. (2006). Self-renewal of embryonic stem cells by a small molecule. Proc Natl Acad Sci U S A. doi:10.1073/pnas.0608156103

Jin, L., Hope, K. J., Zhai, Q., Smadja-Joffe, F., and Dick, J. E. (2006). Targeting of CD44 eradicates human acute myeloid leukemic stem cells. Nat Med 12, 1167-1174.

Kattman, S. J., Huber, T. L., and Keller, G. M. (2006). Multipotent flk-1(+) cardiovascular progenitor cells give rise to the cardiomyocyte, endothelial, and vascular smooth muscle lineages. Dev Cell 11, 723-732.

Krause, D. S., Lazarides, K., von Andrian, U. H., and Van Etten, R. A. (2006). Requirement for CD44 in homing and engraftment of BCR-ABL-expressing leukemic stem cells. Nat Med 12, 1175-1180.

Lepilina, A., Coon, A. N., Kikuchi, K., Holdway, J. E., Roberts, R. W., Burns, C. G., and Poss, K. D. (2006). A Dynamic Epicardial Injury Response Supports Progenitor Cell Activity during Zebrafish Heart Regeneration. Cell 127, 607-619.

Nguyen, H., Rendl, M., and Fuchs, E. (2006). Tcf3 governs stem cell features and represses cell fate determination in skin. Cell 127, 171-183.

Roy, N. S., Cleren, C., Singh, S. K., Yang, L., Beal, M. F., and Goldman, S. A. (2006). Functional engraftment of human ES cell-derived dopaminergic neurons enriched by coculture with telomerase-immortalized midbrain astrocytes. Nat Med 12, 1259-1268.

Singec, I., Knoth, R., Meyer, R. P., Maciaczyk, J., Volk, B., Nikkhah, G., Frotscher, M., and Snyder, E. Y. (2006). Defining the actual sensitivity and specificity of the neurosphere assay in stem cell biology. Nat Methods 3, 801-806.

Sung, L. Y., Gao, S., Shen, H., Yu, H., Song, Y., Smith, S. L., Chang, C. C., Inoue, K., Kuo, L., Lian, J., et al. (2006). Differentiated cells are more efficient than adult stem cells for cloning by somatic cell nuclear transfer. Nat Genet 38, 1323-1328.

Zhang, X., Stojkovic, P., Przyborski, S., Cooke, M., Armstrong, L., Lako, M., and Stojkovic, M. (2006). Derivation of human embryonic stem cells from developing and arrested embryos. Stem Cells. doi: 10.1634/stemcells.2006-0377

August 8, 2006

Policy and Technology:
(2006). The lure of stem-cell lines. Nature 442, 336-337.

Kintisch, E. (2006). Intellectual property. Groups challenge key stem cell patents. Science 313, 281.

Vogel, G. (2006). Stem cells. Team claims success with cow-mouse nuclear transfer. Science 313, 155-156.

Wadman, M., and Abbott, A. (2006). A long week in stem-cell politics. Nature 442, 335.

Commentary:
Enserink, M. (2006). Biomedicine. Selling the stem cell dream. Science 313, 160-163.

Smith, S., Neaves, W., and Teitelbaum, S. (2006). Adult stem cell treatments for diseases? Science 313, 439.

Research Papers:
Forsberg, E. C., Serwold, T., Kogan, S., Weissman, I. L., and Passegue, E. (2006). New evidence supporting megakaryocyte-erythrocyte potential of flk2/flt3(+) multipotent hematopoietic progenitors. Cell 126, 415-426.

Galvez, B. G., Sampaolesi, M., Brunelli, S., Covarello, D., Gavina, M., Rossi, B., Costantin, G., Torrente, Y., and Cossu, G. (2006). Complete repair of dystrophic skeletal muscle by mesoangioblasts with enhanced migration ability. J Cell Biol 174, 231-243.

Jackson, E. L., Garcia-Verdugo, J. M., Gil-Perotin, S., Roy, M., Quinones-Hinojosa, A., Vandenberg, S., and Alvarez-Buylla, A. (2006). PDGFRalpha-Positive B Cells Are Neural Stem Cells in the Adult SVZ that Form Glioma-like Growths in Response to Increased PDGF Signaling. Neuron 51, 187-199.

Krivtsov, A. V., Twomey, D., Feng, Z., Stubbs, M. C., Wang, Y., Faber, J., Levine, J. E., Wang, J., Hahn, W. C., Gilliland, D. G., et al. (2006). Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9. Nature.
      Discussed in: Kesari, S., and Stiles, C. D. (2006).
      The Bad Seed: PDGF Receptors Link Adult Neural Progenitors to Glioma Stem Cells.
      Neuron 51, 151-153.

Nayernia, K., Nolte, J., Michelmann, H. W., Lee, J. H., Rathsack, K., Drusenheimer, N., Dev, A., Wulf, G., Ehrmann, I. E., Elliott, D. J., et al.(2006). In vitro-differentiated embryonic stem cells give rise to male gametes that can generate offspring mice. Dev Cell 11, 125-132.

July 11, 2006

Collections
Nature Insight: Stem Cells (2006). Nature 441, 1059-1102.
Reviews on five areas of stem cell research and progress reports on the use of stem cells as therapy.

Science: Stem Cells Collection (2006). A booklet from Science, produced by the AAAS Office of Publishing and Member Services
Presents key stem cell papers published in Science over the last 8 years

Commentary
Porter, G., Denning, C., Plomer, A., Sinden, J., and Torremans, P. (2006). The patentability of human embryonic stem cells in Europe. Nat Biotechnol 24, 653-655.

Wolpe, P. R. (2006). Reasons scientists avoid thinking about ethics. Cell 125, 1023-1025.

News and Views
Powell, K. (2006). Born or made? Debate on mouse eggs reignites. Nature 441, 795.
Provides commentary on Eggan et al, 2006: see below.

Purton, L. E., and Scadden, D. T. (2006). Osteoclasts eat stem cells out of house and home. Nat Med 12, 610-611.
Provides commentary on Kollet et al, 2006: see below.

Research papers
Eggan, K., Jurga, S., Gosden, R., Min, I. M., and Wagers, A. J. (2006). Ovulated oocytes in adult mice derive from non-circulating germ cells. Nature 441, 1109-1114.

Holmberg, J., Genander, M., Halford, M. M., Anneren, C., Sondell, M., Chumley, M. J., Silvany, R. E., Henkemeyer, M., and Frisen, J. (2006). EphB receptors coordinate migration and proliferation in the intestinal stem cell niche. Cell 125, 1151-1163.

Ivanova, N., Dobrin, R., Lu, R., Kotenko, I., Levorse, J., Decoste, C., Schafer, X., Lun, Y., and Lemischka, I. R. (2006). Dissecting self-renewal in stem cells with RNA interference. Nature.

Kollet, O., Dar, A., Shivtiel, S., Kalinkovich, A., Lapid, K., Sztainberg, Y., Tesio, M., Samstein, R. M., Goichberg, P., Spiegel, A., et al. (2006). Osteoclasts degrade endosteal components and promote mobilization of hematopoietic progenitor cells. Nat Med 12, 657-664.

Rhee, H., Polak, L., and Fuchs, E. (2006). Lhx2 maintains stem cell character in hair follicles. Science 312, 1946-1949.

Rossi, S. W., Jenkinson, W. E., Anderson, G., and Jenkinson, E. J. (2006). Clonal analysis reveals a common progenitor for thymic cortical and medullary epithelium. Nature 441, 988-991.

Silva, J., Chambers, I., Pollard, S., and Smith, A. (2006). Nanog promotes transfer of pluripotency after cell fusion. Nature 441, 997-1001.

June 13, 2006
Review
Rawlins, E. L., and Hogan, B. L. (2006). Epithelial stem cells of the lung: privileged few or opportunities for many? Development 133, 2455-2465

News and Views
Ching, W., and Nusse, R. (2006). A dedicated Wnt secretion factor. Cell 125, 432-433.
Provides commentary on Banziger et al, 2006 and Bartsherer et al, 2006: see below.

Janzen, V., and Scadden, D. T. (2006). Stem cells: good, bad and reformable. Nature 441, 418-419.
Provides commentary on Yilmaz et al, 2006 and Zhang et al, 2006: referenced ahead of print in the May issue of the Pulse.

Research papers
Banziger, C., Soldini, D., Schutt, C., Zipperlen, P., Hausmann, G., and Basler, K. (2006). Wntless, a conserved membrane protein dedicated to the secretion of Wnt proteins from signaling cells. Cell 125, 509-522.

Bartscherer, K., Pelte, N., Ingelfinger, D., and Boutros, M. (2006). Secretion of Wnt ligands requires Evi, a conserved transmembrane protein. Cell 125, 523-533.

Blelloch, R., Wang, Z., Meissner, A., Pollard, S., Smith, A., and Jaenisch, R. (2006). Reprogramming Efficiency following Somatic Cell Nuclear Transfer is Influenced by the Differentiation and Methylation State of the Donor Nucleus. Stem Cells. doi:10.1634/stemcells.2006-0050

Frydman, H. M., Li, J. M., Robson, D. N., and Wieschaus, E. (2006). Somatic stem cell niche tropism in Wolbachia. Nature 441, 509-512.

Kollet, O., Dar, A., Shivtiel, S., Kalinkovich, A., Lapid, K., Sztainberg, Y., Tesio, M., Samstein, R. M., Goichberg, P., Spiegel, A., et al. (2006). Osteoclasts degrade endosteal components and promote mobilization of hematopoietic progenitor cells. Nat Med. 12, 657-664

Lee, J., Kotliarova, S., Kotliarov, Y., Li, A., Su, Q., Donin, N. M., Pastorino, S., Purow, B. W., Christopher, N., Zhang, W., et al. (2006). Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines. Cancer Cell 9, 391-403.

Nolden, L., Edenhofer, F., Haupt, S., Koch, P., Wunderlich, F. T., Siemen, H., and Brustle, O. (2006). Site-specific recombination in human embryonic stem cells induced by cell-permeant Cre recombinase. Nat Methods 3, 461-467.

Shen, Q., Wang, Y., Dimos, J. T., Fasano, C. A., Phoenix, T. N., Lemischka, I. R., Ivanova, N. B., Stifani, S., Morrisey, E. E., and Temple, S. (2006). The timing of cortical neurogenesis is encoded within lineages of individual progenitor cells. Nat Neurosci 9, 743-751.

May 9, 2006

Perspectives
Frank, M. (2006). Access to the scientific literature--a difficult balance. N Engl J Med 354, 1552-1555.

Parson, A. (2006). The long journey from stem cells to medical product. Cell 125, 9-11.

Mini-Review
Buszczak, M., and Spradling, A. C. (2006). Searching chromatin for stem cell identity. Cell 125, 233-236.
Provides commentary on Bernstein et al, 2006, Boyer et al, 2006 and Lee et al, 2006: see below

Research papers
Bernstein, B. E., Mikkelsen, T. S., Xie, X., Kamal, M., Huebert, D. J., Cuff, J., Fry, B., Meissner, A., Wernig, M., Plath, K., et al. (2006). A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell 125, 315-326.

Boyer, L. A., Plath, K., Zeitlinger, J., Brambrink, T., Medeiros, L. A., Lee, T. I., Levine, S. S., Wernig, M., Tajonar, A., Ray, M. K., et al. (2006). Polycomb complexes repress developmental regulators in murine embryonic stem cells. Nature.

Lee, T. I., Jenner, R. G., Boyer, L. A., Guenther, M. G., Levine, S. S., Kumar, R. M., Chevalier, B., Johnstone, S. E., Cole, M. F., Isono, K., et al. (2006). Control of developmental regulators by polycomb in human embryonic stem cells. Cell 125, 301-313.

Lowell, S., Benchoua, A., Heavey, B., and Smith, A. G. (2006). Notch Promotes Neural Lineage Entry by Pluripotent Embryonic Stem Cells. PLoS Biol 4, e121.

Moriyama, M., Osawa, M., Mak, S. S., Ohtsuka, T., Yamamoto, N., Han, H., Delmas, V., Kageyama, R., Beermann, F., Larue, L., and Nishikawa, S. I. (2006). Notch signaling via Hes1 transcription factor maintains survival of melanoblasts and melanocyte stem cells. J Cell Biol.

Noggle, S. A., Weiler, D., and Condie, B. G. (2006). NOTCH signaling is inactive but inducible in human embryonic stem cells. Stem Cells. doi:10.1634/stemcells.2005-0314

Novak, I., Lightfoot, D. A., Wang, H., Eriksson, A., Mahdy, E., and Hoog, C. (2006). Mouse embryonic stem cells form follicle-like ovarian structures but do not progress through meiosis. Stem Cells. doi:10.1634/stemcells.2005-0520

Schaniel, C., Li, F., Schafer, X. L., Moore, T., Lemischka, I. R., and Paddison, P. J. (2006). Delivery of short hairpin RNAs-triggers of gene silencing-into mouse embryonic stem cells. Nat Methods 3, 397-400.

Wong, R. C., Dottori, M., Koh, K. L., Nguyen, L. T., Pera, M. F., and Pebay, A. (2006). Gap junctions modulate apoptosis and colony growth of human embryonic stem cells maintained in a serum-free system. Biochem Biophys Res Commun 344, 181-188.

Woods, N. B., Bottero, V., Schmidt, M., von Kalle, C., and Verma, I. M. (2006). Gene therapy: therapeutic gene causing lymphoma. Nature 440, 1123.

Yao, S., Chen, S., Clark, J., Hao, E., Beattie, G. M., Hayek, A., and Ding, S. (2006). Long-term self-renewal and directed differentiation of human embryonic stem cells in chemically defined conditions. Proc Natl Acad Sci U S A 103, 6907-6912.

Yilmaz, O. H., Valdez, R., Theisen, B. K., Guo, W., Ferguson, D. O., Wu, H., and Morrison, S. J. (2006). Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells. Nature. doi:10.1038/nature04703
Read commentary: Rossi, D. J., and Weissman, I. L. (2006). Pten, tumorigenesis, and stem cell self-renewal. Cell 125, 229-231.

Zhang, J., Grindley, J. C., Yin, T., Jayasinghe, S., He, X. C., Ross, J. T., Haug, J. S., Rupp, D., Porter-Westpfahl, K. S., Wiedemann, L. M., et al. (2006). PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia prevention. Nature.

April 11, 2006

Reviews and perspectives:
Bartunek, J., Dimmeler, S., Drexler, H., Fernandez-Aviles, F., Galinanes, M., Janssens, S., Martin, J., Mathur, A., Menasche, P., Priori, S., et al. (2006). The consensus of the task force of the European Society of Cardiology concerning the clinical investigation of the use of autologous adult stem cells for repair of the heart. Eur Heart J. doi:10.1093/eurheartj/ehi793

Clarke, M. F., and Fuller, M. (2006). Stem cells and cancer: two faces of eve. Cell 124, 1111-1115.

Couzin, J. (2006). Immunology. Diabetes studies conflict on power of spleen cells. Science 311, 1694.

Polyak, K., and Hahn, W. C. (2006). Roots and stems: stem cells in cancer. Nat Med 12, 296-300.

Papers:
Bachoud-Levi, A. C., Gaura, V., Brugieres, P., Lefaucheur, J. P., Boisse, M. F., Maison, P., Baudic, S., Ribeiro, M. J., Bourdet, C., Remy, P., et al. (2006). Effect of fetal neural transplants in patients with Huntington's disease 6 years after surgery: a long-term follow-up study. Lancet Neurol 5, 303-309.
Read commentary:
Rosser, A. E., and Dunnett, S. B. (2006). Cell transplantation for Huntington's disease. Lancet Neurol 5, 284-285.

Betschinger, J., Mechtler, K., and Knoblich, J. A. (2006). Asymmetric segregation of the tumor suppressor brat regulates self-renewal in Drosophila neural stem cells. Cell 124, 1241-1253.
       See also: Lee et al, 2006 (below)
       Read commentary:
       Wodarz, A., and Gonzalez, C. (2006). Connecting cancer to the asymmetric division of stem cells.
       Cell 124, 1121-1123.

Darr, H., Mayshar, Y., and Benvenisty, N. (2006). Overexpression of NANOG in human ES cells enables feeder-free growth while inducing primitive ectoderm features. Development 133, 1193-1201.

Dyce, P. W., Wen, L., and Li, J. (2006). In vitro germline potential of stem cells derived from fetal porcine skin. Nat Cell Biol. 8, 384-390

Guan, K., Nayernia, K., Maier, L. S., Wagner, S., Dressel, R., Lee, J. H., Nolte, J., Wolf, F., Li, M., Engel, W., and Hasenfuss, G. (2006). Pluripotency of spermatogonial stem cells from adult mouse testis. Nature doi:10.1038/nature04697

Ito, K., Hirao, A., Arai, F., Takubo, K., Matsuoka, S., Miyamoto, K., Ohmura, M., Naka, K., Hosokawa, K., Ikeda, Y., and Suda, T. (2006). Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells. Nat Med. 446-451
Read commentary:
Liu, J. and Finkel, T. (2006). Stem cell aging: what bleach can teach. Nature Medicine 12 , 383-384

Kaji, K., Caballero, I. M., MacLeod, R., Nichols, J., Wilson, V. A., and Hendrich, B. (2006). The NuRD component Mbd3 is required for pluripotency of embryonic stem cells. Nat Cell Biol 8, 285-292.

Lee, C. Y., Wilkinson, B. D., Siegrist, S. E., Wharton, R. P., and Doe, C. Q. (2006). Brat is a Miranda Cargo Protein that Promotes Neuronal Differentiation and Inhibits Neuroblast Self-Renewal. Dev Cell. 10 441-449
See also: Lee et al, 2006 and commentary in Wodarz and Gonzalez, 2006 (above)

Loh, Y. H., Wu, Q., Chew, J. L., Vega, V. B., Zhang, W., Chen, X., Bourque, G., George, J., Leong, B., Liu, J., et al. (2006). The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells. Nat Genet 38, 431-440.

Loring, J. F., and Campbell, C. (2006). Science and law. Intellectual property and human embryonic stem cell research. Science 311, 1716-1717.

Yang, W., Klaman, L. D., Chen, B., Araki, T., Harada, H., Thomas, S. M., George, E. L., and Neel, B. G. (2006). An Shp2/SFK/Ras/Erk signaling pathway controls trophoblast stem cell survival. Dev Cell 10, 317-327.
Read commentary:
Ralston, A., and Rossant, J. (2006). How signaling promotes stem cell survival: trophoblast stem cells and Shp2. Dev Cell 10, 275-276.

Yoshida, S., Sukeno, M., Nakagawa, T., Ohbo, K., Nagamatsu, G., Suda, T., and Nabeshima, Y. (2006). The first round of mouse spermatogenesis is a distinctive program that lacks the self-renewing spermatogonia stage. Development 133, 1495-1505.

March 14, 2006

Thoughts for junior investigators:
Aschwanden, C. (2006). Professionalizing the postdoctoral experience. Cell 124, 445-447.

New rules for data-imaging:
(2006). Not picture-perfect. Nature 439, 891-892.

Perspectives:
Goozner, M. (2006). Innovation in Biomedicine: Can Stem Cell Research Lead the Way to Affordability? PLoS Med 3, e126.

An interesting technique:
So, M. K., Xu, C., Loening, A. M., Gambhir, S. S., and Rao, J. (2006). Self-illuminating quantum dot conjugates for in vivo imaging. Nat Biotechnol. doi:10.1038/nbt1188

Research papers:
Armakolas, A., and Klar, A. J. (2006). Cell type regulates selective segregation of mouse chromosome 7 DNA strands in mitosis. Science 311, 1146-1149.

Hao, E., Tyrberg, B., Itkin-Ansari, P., Lakey, J. R., Geron, I., Monosov, E. Z., Barcova, M., Mercola, M., and Levine, F. (2006). Beta-cell differentiation from nonendocrine epithelial cells of the adult human pancreas. Nat Med 12, 310-316.

Herszfeld, D., Wolvetang, E., Langton-Bunker, E., Chung, T. L., Filipczyk, A. A., Houssami, S., Jamshidi, P., Koh, K., Laslett, A. L., Michalska, A., et al. (2006). CD30 is a survival factor and a biomarker for transformed human pluripotent stem cells. Nat Biotechnol. 24, 344-350.

Okutsu, T., Suzuki, K., Takeuchi, Y., Takeuchi, T., and Yoshizaki, G. (2006). Testicular germ cells can colonize sexually undifferentiated embryonic gonad and produce functional eggs in fish. Proc Natl Acad Sci U S A. doi:10.1073/pnas.0509218103

Taylor, R. A., Cowin, P. A., Cunha, G. R., Pera, M., Trounson, A. O., Pedersen, J., and Risbridger, G. P. (2006). Formation of human prostate tissue from embryonic stem cells. Nat Methods 3, 179-181.

February 15, 2006

Perspectives on egg donations and ES cell research:
Steinbrook, R. (2006). Egg donation and human embryonic stem-cell research. N Engl J Med 354, 324-326.

See also: News Feature in the Feb. 9 issue of Nature 439, 652-657

Articles:
Andersson, E., Tryggvason, U., Deng, Q., Friling, S., Alekseenko, Z., Robert, B., Perlmann, T., and Ericson, J. (2006). Identification of intrinsic determinants of midbrain dopamine neurons. Cell 124, 393-405.

Burns, T. C., Ortiz-Gonzalez, X. R., Gutierrez-Perez, M., Keene, C. D., Sharda, R., Demorest, Z. L., Jiang, Y., Nelson-Holte, M., Soriano, M., Nakagawa, Y., et al. (2006). Thymidine Analogs are Transferred from Pre-Labeled Donor to Host Cells in the Central Nervous System After Transplantation: A Word of Caution. Stem Cells.

Kalantry, S., Mills, K. C., Yee, D., Otte, A. P., Panning, B., and Magnuson, T. (2006). The Polycomb group protein Eed protects the inactive X-chromosome from differentiation-induced reactivation. Nat Cell Biol 8, 195-202.

Katayama, Y., Battista, M., Kao, W. M., Hidalgo, A., Peired, A. J., Thomas, S. A., and Frenette, P. S. (2006). Signals from the sympathetic nervous system regulate hematopoietic stem cell egress from bone marrow. Cell 124, 407-421.
Read commentary in:
Larsson, J., and Scadden, D. (2006). Nervous activity in a stem cell niche. Cell 124, 253-255.

Lee, C. Y., Robinson, K. J., and Doe, C. Q. (2006). Lgl, Pins and aPKC regulate neuroblast self-renewal versus differentiation. Nature 439, 594-598.

Meshorer, E., Yellajoshula, D., George, E., Scambler, P. J., Brown, D. T., and Misteli, T. (2006). Hyperdynamic plasticity of chromatin proteins in pluripotent embryonic stem cells. Dev Cell 10, 105-116.
Read commentary in:
Zwaka, T. P. (2006). Breathing chromatin in pluripotent stem cells. Dev Cell 10, 1-2.

Pyle, A. D., Lock, L. F., and Donovan, P. J. (2006). Neurotrophins mediate human embryonic stem cell survival. Nat Biotechnol.

Shackleton, M., Vaillant, F., Simpson, K. J., Stingl, J., Smyth, G. K., Asselin-Labat, M. L., Wu, L., Lindeman, G. J., and Visvader, J. E. (2006). Generation of a functional mammary gland from a single stem cell. Nature 439, 84-88.

Stingl, J., Eirew, P., Ricketson, I., Shackleton, M., Vaillant, F., Choi, D., Li, H. I., and Eaves, C. J. (2006). Purification and unique properties of mammary epithelial stem cells. Nature.

Trowbridge, J. J., Xenocostas, A., Moon, R. T., and Bhatia, M. (2006). Glycogen synthase kinase-3 is an in vivo regulator of hematopoietic stem cell repopulation. Nat Med 12, 89-98.

Wang, H., Singh, S. R., Zheng, Z., Oh, S. W., Chen, X., Edwards, K., and Hou, S. X. (2006). Rap-GEF signaling controls stem cell anchoring to their niche through regulating DE-cadherin-mediated cell adhesion in the Drosophila testis. Dev Cell 10, 117-126.

Wu, S., Wu, Y., and Capecchi, M. R. (2006). Motoneurons and oligodendrocytes are sequentially generated from neural stem cells but do not appear to share common lineage-restricted progenitors in vivo. Development 133, 581-590.

Zhang, C. C., Kaba, M., Ge, G., Xie, K., Tong, W., Hug, C., and Lodish, H. F. (2006). Angiopoietin-like proteins stimulate ex vivo expansion of hematopoietic stem cells. Nat Med 12, 240-245.

January 5, 2006

Looking back over 2005:
Culotta, E., and Pennisi, E. (2005). Breakthrough of the year: evolution in action. Science 310, 1878-1879.

(2005a). Breakthrough of the year: scorecard 2004. Science 310, 1880.

(2005b). Breakthrough of the year: the runners-up. Science 310, 1880-1885.

Reviews:
Brockes, J. P., and Kumar, A. (2005). Appendage regeneration in adult vertebrates and implications for regenerative medicine. Science 310, 1919-1923.

Muller, F. J., Snyder, E. Y., and Loring, J. F. (2006). Gene therapy: can neural stem cells deliver? Nat Rev Neurosci 7, 75-84.

Papers:
Adams, G. B., Chabner, K. T., Alley, I. R., Olson, D. P., Szczepiorkowski, Z. M., Poznansky, M. C., Kos, C. H., Pollak, M. R., Brown, E. M., and Scadden, D. T. (2005). Stem cell engraftment at the endosteal niche is specified by the calcium-sensing receptor. Nature.

Damelin, M., Sun, Y. E., Sodja, V. B., and Bestor, T. H. (2005). Decatenation checkpoint deficiency in stem and progenitor cells. Cancer Cell 8, 479-484.

Ge, S., Goh, E. L., Sailor, K. A., Kitabatake, Y., Ming, G. L., and Song, H. (2005). GABA regulates synaptic integration of newly generated neurons in the adult brain. Nature.

Kaplan, R. N., Riba, R. D., Zacharoulis, S., Bramley, A. H., Vincent, L., Costa, C., MacDonald, D. D., Jin, D. K., Shido, K., Kerns, S. A., et al. (2005). vEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche. Nature 438, 820-827.

Laird, D. J., De Tomaso, A. W., and Weissman, I. L. (2005). Stem cells are units of natural selection in a colonial ascidian. Cell 123, 1351-1360.

Ludwig, T. E., Levenstein, M. E., Jones, J. M., Berggren, W. T., Mitchen, E. R., Frane, J. L., Crandall, L. J., Daigh, C. A., Conard, K. R., Piekarczyk, M. S., et al. (2006). Derivation of human embryonic stem cells in defined conditions. Nat Biotechnol.

Micchelli, C. A., and Perrimon, N. (2005). Evidence that stem cells reside in the adult Drosophila midgut epithelium. Nature.

Muotri, A. R., Nakashima, K., Toni, N., Sandler, V. M., and Gage, F. H. (2005). Development of functional human embryonic stem cell-derived neurons in mouse brain. Proc Natl Acad Sci U S A 102, 18644-18648.

Ohlstein, B., and Spradling, A. (2005). The adult Drosophila posterior midgut is maintained by pluripotent stem cells. Nature.

Samakoglu, S., Lisowski, L., Budak-Alpdogan, T., Usachenko, Y., Acuto, S., Di Marzo, R., Maggio, A., Zhu, P., Tisdale, J. F., Riviere, I., and Sadelain, M. (2005). A genetic strategy to treat sickle cell anemia by coregulating globin transgene expression and RNA interference. Nat Biotechnol.

Taylor, C. J., Bolton, E. M., Pocock, S., Sharples, L. D., Pedersen, R. A., and Bradley, J. A. (2005). Banking on human embryonic stem cells: estimating the number of donor cell lines needed for HLA matching. Lancet 366, 2019-2025.

Weinand, C., Pomerantseva, I., Neville, C. M., Gupta, R., Weinberg, E., Madisch, I., Shapiro, F., Abukawa, H., Troulis, M. J., and Vacanti, J. P. (2005). Hydrogel-beta-TCP scaffolds and stem cells for tissue engineering bone. Bone.

Wildwater, M., Campilho, A., Perez-Perez, J. M., Heidstra, R., Blilou, I., Korthout, H., Chatterjee, J., Mariconti, L., Gruissem, W., and Scheres, B. (2005). The RETINOBLASTOMA-RELATED Gene Regulates Stem Cell Maintenance in Arabidopsis Roots. Cell 123, 1337-1349. or read comments in: Dinneny, J. R., and Benfey, P. N. (2005). Stem Cell Research Goes Underground: The RETINOBLASTOMA-RELATED Gene in Root Development. Cell 123, 1180-1182.

Updated: December 9, 2008

Disclaimers | Privacy Information | Contact Us | Site Map